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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

Items 661-670 of 1733

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  1. BIBR 953 (Dabigatran, Pradaxa)
    A4077 BIBR 953 (Dabigatran, Pradaxa)
    Summary: Thrombin inhibitor,potent,reversible and direct
      insoluble in DMSO; insoluble in EtOH; insoluble in H2O
  2. EPZ005687
    A4171 EPZ005687
     2 Citation
    Target: EZH2
    Summary: EZH2 inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥3.86 mg/mL
  3. Glimepiride
    A4033 Glimepiride
    Target: Inward Rectifier Potassium (Kir) Channels
    Summary: Sulfonylurea compound
      ≥21.45 mg/mL
  4. AR-42 (OSU-HDAC42)
    A4104 AR-42 (OSU-HDAC42)
     2 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor,novel and potent
      insoluble in EtOH; insoluble in H2O; ≥15.62 mg/mL
  5. Hesperadin
    A4118 Hesperadin
     1 Citation
    Target: Aurora Kinases
    Summary: Aurora B kinase inhibitor
      ≥25.85 mg/mL
  6. Thalidomide
    A4216 Thalidomide
    Target: Ubiquitin E3 Ligases
    Summary: Immunomodulatory agent,sedative drug,angiogenesis inhibitor
      insoluble in H2O; insoluble in EtOH; ≥11.8 mg/mL
  7. Tipifarnib (Zarnestra)
    A4227 Tipifarnib (Zarnestra)
    Summary: Farnesyltransferase inhibitor,potent and specific
      insoluble in H2O; ≥8.16 mg/mL
  8. NSC 66811
    A4230 NSC 66811
    Summary: MDM2 inhibitor
      ≥34 mg/mL
  9. Ketoconazole
    A4316 Ketoconazole
    Target: Cytochrome P450 (CYP450)
    Summary: Inhibitor of cyclosporine oxidase and testosterone 6 beta-hydroxylase
      ≥23.4 mg/mL
  10. Avasimibe
    A4318 Avasimibe
    Target: Acyl coenzyme A: cholesterol acyltransferases
    Summary: ACAT inhibitor,orally bioavailable
      ≥25.09 mg/mL

Items 661-670 of 1733

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Category
  1. Proteases 79item
  2. Apoptosis 88item
  3. Chromatin/Epigenetics 118item
  4. Metabolism 86item
  5. MAPK Signaling 76item
  6. Tyrosine Kinase 115item
  7. DNA Damage/DNA Repair 75item
  8. PI3K/Akt/mTOR Signaling 125item
  9. Microbiology & Virology 69item
  10. Cell Cycle/Checkpoint 80item
  11. Ubiquitination/ Proteasome 21item
  12. JAK/STAT Signaling 44item
  13. TGF-β / Smad Signaling 46item
  14. Angiogenesis 21item
  15. GPCR/G protein 218item
  16. Stem Cell 63item
  17. Membrane Transporter/Ion Channel 103item
  18. Cancer Biology 15item
  19. Endocrinology and Hormones 45item
  20. Neuroscience 148item
  21. Obesity, Appetite Control & Diabetes 4item
  22. Peptide Inhibitors and Substrate 1 item
  23. Other Signal Transduction 44item
  24. Others 189item
  25. Immunology/Inflammation 38item
  26. Cardiovascular 25item
  27. Vitamin D Related 9item
  28. NF-κB 2item
  29. Autophagy 2item
  30. Metabolic Enzyme/Protease 30item
  31. Alkaloids 1 item
  32. Anti-infection 10item
  33. Cell Cycle/DNA Damage 2item
  34. Neuronal Signaling 2item
  35. Terpenoids and Glycosides 1 item
Specificity
  1. Selective 388item
  2. Non-Selective 2item
Reversibility
  1. Reversible 23item
  2. Irreversible 9item
Target
  1. Caspases 6item
  2. Cyclin-Dependent Kinases 16item
  3. Adenosine A2A Receptors 1 item
  4. Proteasome 2item
  5. Cathepsins 3item
  6. Histone Deacetylases (HDACs) 12item
  7. Inhibitor of apoptosis proteins (IAP) 1 item
  8. Akt 12item
  9. Bcl-2 8item
  10. PI3K 33item
  11. CXCR 1 item
  12. Raf 9item
  13. Aurora Kinases 7item
  14. Bcl-xl 2item
  15. CSF-1R 1 item
  16. Gap Junctions 2item
  17. MDM2 2item
  18. EZH2 3item
  19. mTOR 19item
  20. Bromodomains 3item
  21. AP-1 3item
  22. MMP 8item
  23. Androgen Receptors 4item
  24. Acyl coenzyme A: cholesterol acyltransferases 1 item
  25. FLT3 11item
  26. GSK-3 9item
  27. Factor Xa 1 item
  28. LPA Receptors 3item
  29. P-glycoprotein (P-gp) 1 item
  30. PLK 6item
  31. Chk 4item
  32. VEGFR 24item
  33. PDGFR 14item
  34. c-Kit 6item
  35. RET 3item
  36. IRAK 3item
  37. Bromodomain-containing proteins(BRDs) 1 item
  38. Phosphodiesterases (PDEs) 2item
  39. Mcl-1 7item
  40. p38 6item
  41. PKB 1 item
  42. JNK 5item
  43. SGK 2item
  44. Bcr-Abl 7item
  45. MEK 11item
  46. PORCN 1 item
  47. DOT1L 1 item
  48. FGFR 4item
  49. Insulin-like growth factor receptors(IGFRs) 1 item
  50. CGRP receptors 1 item
  51. Pim 2item
  52. GABAB Receptors 1 item
  53. Liver X receptors (LXRs) 1 item
  54. Glucagon-like peptide 1 (GLP-1) receptors 2item
  55. Sir2-like Family Deacetylases (Sirtuins) 3item
  56. Voltage-gated Sodium (NaV) Channels 1 item
  57. Deubiquitinating enzymes (DUBs) 2item
  58. PP1 1 item
  59. PP2A 1 item
  60. Smoothened 2item
  61. Eukaryotic elongation factors 1 item
  62. MET 1 item
  63. Src 9item
  64. Trk Receptors 3item
  65. Aminopeptidases 3item
  66. NMDA Receptors 2item
  67. STAT 7item
  68. Microtubules/Tubulins 4item
  69. Estrogen and Related Receptors 2item
  70. EGFR 4item
  71. Hedgehog 1 item
  72. Reverse Transcriptases 1 item
  73. ROCK 3item
  74. BTK 1 item
  75. RIP kinases 1 item
  76. PAK 1 item
  77. PD-1/PD-L1 interaction 1 item
  78. Hypoxia Inducible Factors (HIFs) 1 item
  79. BMP and Other Activin Receptors 2item
  80. JAK 10item
  81. p300 1 item
  82. Stearoyl-CoA 9-desaturase (SCD-1) 1 item
  83. Syk 3item
  84. Progesterone Receptors 1 item
  85. EZH1 1 item
  86. DNA-PK 6item
  87. HSP90 2item
  88. AMPK 1 item
  89. Gutathione S-transferase 1 item
  90. CCR 2item
  91. eIF4E/eIF3G interaction 1 item
  92. TNKS 1 item
  93. Topoisomerases 5item
  94. Cytochrome P450 (CYP450) 4item
  95. Ferroptosis 1 item
  96. Toll-like receptors (TLRs) 3item
  97. Actin 1 item
  98. DNA Methyltransferases 2item
  99. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  100. ERK 5item
  101. HMG-CoA Reductases 1 item
  102. Vacuolar-type ATPase 1 item
  103. c-MET 3item
  104. BMI-1 1 item
  105. PKC 8item
  106. Calpains 2item
  107. M1 Receptors 1 item
  108. HCV Proteases 1 item
  109. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  110. Protease-Activated Receptors 2item
  111. RAD51 1 item
  112. USP 1 item
  113. 5-HT2 Receptors 3item
  114. LRRK2 2item
  115. Calcium chelator 1 item
  116. DGAT 2item
  117. Insulin and Insulin-like Receptors 2item
  118. PARP 5item
  119. CB1 Receptors 2item
  120. Melanocortin (MC) Receptors 1 item
  121. ALK 2item
  122. Sphingosine kinases (SphKs) 2item
  123. Trypsin 1 item
  124. Chymotrypsin 1 item
  125. Kallikrein 1 item
  126. Trypsinogen 1 item
  127. Monocarboxylate transporters (MCTs) 2item
  128. PKG 1 item
  129. PKA 5item
  130. GPR30 1 item
  131. HIV-1 gp120 1 item
  132. D2 Receptors 1 item
  133. TBK1 1 item
  134. MARK1 1 item
  135. NUAK1 1 item
  136. Lactate Dehydrogenases (LDH) 1 item
  137. MK2 2item
  138. Fatty-acid-binding proteins (FABPs) 1 item
  139. Tie-2 2item
  140. RSK 1 item
  141. Free Fatty Acid Receptors 1 item
  142. phosphatases 1 item
  143. Autophagy 3item
  144. ATM/ATR 3item
  145. COX 6item
  146. YAP 1 item
  147. CK1 2item
  148. CK2 1 item
  149. HIV Integrases 1 item
  150. Cryptochromes 1 item
  151. G-quadruplexes 1 item
  152. NAT10 1 item
  153. Nampt 1 item
  154. P2X Receptors 1 item
  155. Glutaminases 1 item
  156. Carbonic Anhydrases 2item
  157. Ron 1 item
  158. BLM 1 item
  159. HSV 2item
  160. NADPH Oxidases 1 item
  161. Calcium-activated chloride channels (CaCC) 1 item
  162. GPR35 1 item
  163. Aldehyde Dehydrogenases 1 item
  164. Synthases/Synthetases 1 item
  165. MAGL 1 item
  166. c-Fyn 1 item
  167. Leukotriene and Related Receptors 1 item
  168. Histamine H1 Receptors 2item
  169. RAR/RXR 1 item
  170. Inositol-requiring enzyme 1 (IRE1) 1 item
  171. SETD7 1 item
  172. Na /K /Cl- Symporters (NKCCs) 1 item
  173. TRP Channel 2item
  174. RNA Polymerases 1 item
  175. Norepinephrine transporter 1 item
  176. 5-HT Transporters 1 item
  177. Guanylyl Cyclases 1 item
  178. Histone Demethylases 1 item
  179. MNK 2item
  180. NO Donors / Precursors 1 item
  181. CB2 Receptors 1 item
  182. HIV-1 reverse transcriptase 1 item
  183. IL Receptors 1 item
  184. 15-lipoxygenases 1 item
  185. AChE 1 item
  186. Insulin Receptors 1 item
  187. IRG-1R 1 item
  188. eEF-2 1 item
  189. Inward Rectifier Potassium (Kir) Channels 1 item
  190. CRTH2 1 item
  191. Nuclear Receptors 1 item
  192. ZAP-70 1 item
  193. Angiotensin AT1 Receptors 2item
  194. Protein Arginine Methyltransferases 1 item
  195. Na /Ca2 Exchangers (NCXs) 1 item
  196. Ubiquitin-activating Enzyme E1 1 item
  197. BACE 1 item
  198. Glucagon Receptors 1 item
  199. PP4 1 item
  200. c-RET 1 item
  201. Nonstructural protein 5B (NS5B) 1 item
  202. guanylyl cyclase 1 item
  203. ETA Receptors 2item
  204. ETB Receptors 1 item
  205. p70 rsk 3item
  206. voltage-gated chloride channels 1 item
  207. 5-HT1 Receptor 1 item
  208. VEGFR3/FLT4 1 item
  209. NTRK1/TRKA 1 item
  210. CSF-1R/c-Fms 1 item
  211. Menin-MLL 2item
  212. Tryptophan hydroxylases (TPH) 1 item
  213. NMPRTase 1 item
  214. Bfl-1 1 item
  215. sodium channels 1 item
  216. KDR 1 item
  217. Fyn kinase 1 item
  218. dCTP Pyrophosphatases 1 item
  219. Protein polybromo-1 1 item
  220. SMARCA4 1 item
  221. SMARCA2 1 item
  222. p53 4item
  223. metalloprotease 1 item
  224. Antifungal 1 item
  225. 5-HT receptors 1 item
  226. sodium channel 1 item
  227. c-Fms tyrosine kinase 1 item
  228. PAR 1 item
  229. Smoothened receptor 1 item
  230. Nrf2/ARE signal 1 item
  231. PPAR 2item
  232. USP1/USF1 complex 1 item
  233. IKK 1 item
  234. TRPV 1 item
  235. Ftase 1 item
  236. Elastases 1 item
  237. ATP synthase 1 item
  238. Vitamin D receptors (VDRs) 1 item
  239. Antibiotic 3item
  240. Mer tyrosine kinase 1 item
  241. Hec1 1 item
  242. Stem Cell Differentiation 1 item
  243. PP2A/Nkd interaction 1 item
  244. HMGCR 1 item
  245. HIV 1 item
  246. TRPA 1 item
  247. PDK-1 1 item
  248. telomerase 1 item
  249. Prk 1 item
  250. Trx 1 item
  251. Neurokinin receptor 1 item
  252. HSP70 1 item
  253. ICAM 1 item
  254. ITK 1 item
  255. NOD1 1 item
  256. Rho 1 item
  257. Aryl hydrocarbon receptors (AHRs) 1 item
  258. Ubiquitin E3 Ligases 1 item
  259. DCLK2 1 item
  260. integrase 1 item
  261. L3MBTL 1 item
  262. NOS 1 item
  263. GPR3 1 item
  264. Lck 1 item
  265. Adenosine Deaminases 1 item
  266. mitochondrial pyruvate carrier (MPC) 1 item
  267. DNA gyrase 1 item
  268. Thrombin Receptor 1 item
  269. prolactin secretion 1 item
  270. gonadotropin release 1 item
  271. DprE 1 item
  272. Vitamin D 1 item
  273. Flk1 1 item
  274. SAPK 1 item
  275. p21 1 item
  276. Prostaglandin synthesis 1 item
  277. glutamate release 1 item
  278. Aromatases 1 item
  279. 5-HT 1 item
  280. TRPC channel 1 item
  281. PKD 1 item
  282. Octamer-binding transcription factor 4 (Oct4) 1 item
  283. FKBP 1 item
  284. MCL1 1 item
  285. Bcl-w 1 item
  286. ACE 1 item
  287. MST 1 item
  288. PPK 1 item
  289. c-Syk 1 item
  290. CDK1/CyclinB 1 item
  291. Tph 1 item
  292. reverse transcriptase 1 item
  293. Cholesterol absorption 1 item
  294. Substance P/NK1 Receptor 1 item
  295. gp120/CD4 1 item
  296. ATM 2item
  297. PTEN 1 item
  298. NS3/4a Proteases 1 item
  299. p90 S6K 1 item
Reported Experiments
  1. Animal Experiments 486item
  2. Cell Experiments 393item
Related Disease
  1. Abscesses And Esophageal Candidiasis 1 item
  2. Acute Disseminated Candidiasis 1 item
  3. Acute Lung Injury 1 item
  4. Acute Myelogenous Leukemia 1 item
  5. Acute Myeloid Leukemia 10item
  6. Adrenocortical Carcinoma 1 item
  7. Advanced Renal Cell Carcinoma 1 item
  8. Autoimmune Diseases 1 item
  9. Biliary Cancer 1 item
  10. Bladder Cancer 3item
  11. Bladder Carcinoma 1 item
  12. Bladder Diseases 1 item
  13. Brain Injuries Studies 1 item
  14. Breast Cancer 60item
  15. Cancer 265item
  16. Candida Peritonitis 1 item
  17. Candidemia 1 item
  18. Cervical Cancer 4item
  19. Cholangiocarcinoma 1 item
  20. Chronic Lymphocytic Leukemia 3item
  21. Clear Cell Renal Cell Carcinoma 1 item
  22. Colon Cancer 22item
  23. Colon Carcinoma 5item
  24. Colorectal Cancer 26item
  25. Diabetes 3item
  26. Epilepsy 3item
  27. Fungal Infection 1 item
  28. Glioblastoma 18item
  29. Glioma 10item
  30. HCV 1 item
  31. Heart Failure 3item
  32. Hepatic Cancer 1 item
  33. Hepatitis C 2item
  34. Hepatocellular Carcinoma 3item
  35. HIV 8item
  36. HIV Infections 4item
  37. Hypercholesterolemia 2item
  38. Inflammatory Diseases 9item
  39. Leukemia 15item
  40. Liver Cancer 1 item
  41. Lung Cancer 19item
  42. Lung Carcinoma 2item
  43. Lymphoma 15item
  44. Medulloblastoma 1 item
  45. Melanoma 19item
  46. Mixed Lineage Leukemia 1 item
  47. Multiple Myeloma 7item
  48. Myelofibrosis 1 item
  49. Myeloma 3item
  50. Neuroblastoma 4item
  51. Non-small Cell Lung Cancer 15item
  52. Non-small Cell Lung Carcinoma 1 item
  53. Osteoporosis 1 item
  54. Ovarian Cancer 18item
  55. Pancreatic Cancer 25item
  56. Pancreatic Carcinoma 3item
  57. Pentacyclic Triterpenoid 1 item
  58. Prostate Cancer 32item
  59. Psoriasis 1 item
  60. Pulmonary Arterial Hypertension 1 item
  61. Pulmonary Fibrosis 1 item
  62. Renal Cancer 3item
  63. Renal Cell Carcinoma 4item
  64. Rheumatoid Arthritis 6item
  65. Schizophrenia 1 item
  66. Sleep Disorders 1 item
  67. Squamous Cell Carcinoma 1 item
  68. Testicular Cancer 1 item
  69. Thyroid Cancer 4item
  70. Tuberculosis 4item
  71. Type 2 Diabetes 10item