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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

Items 1-10 of 45

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  1. Tenovin-1
    A4203 Tenovin-1
    Target: Sir2-like Family Deacetylases (Sirtuins)|p53|p21
    Summary: SIRT2 inhibitor, activates p53
      insoluble in H2O; insoluble in EtOH; ≥15 mg/mL
  2. Sephin1
    A8708 Sephin1
     1 Citation
    Target: phosphatases
    Summary: Selective PPP1R15A inhibitor
      insoluble in H2O; insoluble in EtOH; ≥7.75 mg/mL
  3. PFI-1 (PF-6405761)
    A4184 PFI-1 (PF-6405761)
     1 Citation
    Target: Bromodomains
    Summary: BET inhibitor
      insoluble in H2O; insoluble in EtOH; ≥128.4 mg/mL
  4. Cucurbitacin I
    A4512 Cucurbitacin I
    Target: STAT|JAK
    Summary: STAT3/JAK2 signaling inhibitor
      ≥22.45 mg/mL
  5. WP1066
    A4140 WP1066
    Target: STAT|JAK
    Summary: JAK2/STAT3 inhibitor,cell-permeable
      insoluble in H2O; ≥17.8 mg/mL
  6. Bromodomain Inhibitor, (+)-JQ1
    A1910 Bromodomain Inhibitor, (+)-JQ1
     38 Citation
    Target: Bromodomains
    Summary: BET bromodomain inhibitor
      ≥22.85 mg/mL
  7. XAV-939
    A1877 XAV-939
     1 Citation
    Target: TNKS
    Summary: Tankyrase 1/2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15.62 mg/mL
  8. BAY 87-2243
    B1115 BAY 87-2243
    Target: Hypoxia Inducible Factors (HIFs)
    Summary: HIF-1 inhibitor,potent and selective
  9. CUDC-907
    A4097 CUDC-907
    Target: Histone Deacetylases (HDACs)|PI3K
    Summary: Potent PI3K/HDAC inhibitor
      ≥25.45 mg/mL
  10. PJ34
    A3729 PJ34
    Target: PARP
    Summary: PARP-l inhibitor
      ≥50.9 mg/mL

Items 1-10 of 45

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  1. Category Chromatin/Epigenetics Remove This Item
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Category
  1. Bromodomain 2item
  2. Aurora Kinase 4item
  3. HDAC 12item
  4. Histone Acetyltransferases 1 item
  5. Histone Demethylases 1 item
  6. Histone Methyltransferase 2item
  7. HIF 3item
  8. JAK 8item
  9. PARP 6item
  10. Pim 1 item
  11. Protein Ser/Thr Phosphatases 2item
  12. Sirtuin 3item
Specificity
  1. Selective 30item
Reversibility
  1. Reversible 1 item
  2. Irreversible 1 item
Target
  1. Histone Deacetylases (HDACs) 11item
  2. PI3K 1 item
  3. Aurora Kinases 4item
  4. MDM2 1 item
  5. Bromodomains 2item
  6. FLT3 3item
  7. VEGFR 1 item
  8. RET 1 item
  9. DOT1L 1 item
  10. Pim 1 item
  11. Sir2-like Family Deacetylases (Sirtuins) 3item
  12. PP1 1 item
  13. PP2A 1 item
  14. Src 1 item
  15. STAT 2item
  16. Hypoxia Inducible Factors (HIFs) 1 item
  17. JAK 8item
  18. p300 1 item
  19. TNKS 1 item
  20. Topoisomerases 1 item
  21. DNA Methyltransferases 1 item
  22. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  23. PARP 5item
  24. phosphatases 1 item
  25. Histone Demethylases 1 item
  26. MNK 1 item
  27. Protein Arginine Methyltransferases 1 item
  28. PP4 1 item
  29. c-RET 1 item
  30. VEGFR3/FLT4 1 item
  31. NTRK1/TRKA 1 item
  32. CSF-1R/c-Fms 1 item
  33. p53 2item
  34. Trx 1 item
  35. p21 1 item
  36. 5-HT 1 item
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  3. Cancer 29item
  4. Cervical Cancer 1 item
  5. Colon Cancer 4item
  6. Colon Carcinoma 1 item
  7. Colorectal Cancer 1 item
  8. Epilepsy 1 item
  9. Glioblastoma 1 item
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  11. Hepatic Cancer 1 item
  12. Hepatocellular Carcinoma 1 item
  13. Inflammatory Diseases 1 item
  14. Leukemia 2item
  15. Lung Cancer 1 item
  16. Lymphoma 1 item
  17. Melanoma 1 item
  18. Mixed Lineage Leukemia 1 item
  19. Multiple Myeloma 2item
  20. Myelofibrosis 1 item
  21. Non-small Cell Lung Cancer 3item
  22. Ovarian Cancer 3item
  23. Pancreatic Cancer 2item
  24. Prostate Cancer 4item
  25. Renal Cell Carcinoma 1 item
  26. Rheumatoid Arthritis 1 item