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  • Search results for: 'research area pi3k akt signaling pdk 1'

Search results for: 'research area pi3k akt signaling pdk 1'

Items 1-10 of 39

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  1. Sephin1
    A8708 Sephin1
     1 Citation
    Target: phosphatases
    Summary: Selective PPP1R15A inhibitor
      insoluble in H2O; insoluble in EtOH; ≥7.75 mg/mL
  2. PFI-1 (PF-6405761)
    A4184 PFI-1 (PF-6405761)
     1 Citation
    Target: Bromodomains
    Summary: BET inhibitor
      insoluble in H2O; insoluble in EtOH; ≥128.4 mg/mL
  3. Cucurbitacin I
    A4512 Cucurbitacin I
    Target: STAT|JAK
    Summary: STAT3/JAK2 signaling inhibitor
      ≥22.45 mg/mL
  4. XAV-939
    A1877 XAV-939
     1 Citation
    Target: TNKS
    Summary: Tankyrase 1/2 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥15.62 mg/mL
  5. BAY 87-2243
    B1115 BAY 87-2243
    Target: Hypoxia Inducible Factors (HIFs)
    Summary: HIF-1 inhibitor,potent and selective
  6. CUDC-907
    A4097 CUDC-907
    Target: Histone Deacetylases (HDACs)|PI3K
    Summary: Potent PI3K/HDAC inhibitor
      ≥25.45 mg/mL
  7. PJ34
    A3729 PJ34
    Target: PARP
    Summary: PARP-l inhibitor
      ≥50.9 mg/mL
  8. ZM 447439
    A4113 ZM 447439
    Target: Aurora Kinases|MEK|Src|Lck
    Summary: Aurora Kinase inhibitor,potent and selective
      ≥25.7 mg/mL
  9. DMOG
    A4506 DMOG
    Target: Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs)
    Summary: Competitive HIF-PH inhibitor, cell-permeable
  10. Inauhzin
    B3272 Inauhzin
    Target: Sir2-like Family Deacetylases (Sirtuins)
    Summary: SIRT1 inhibitor
      ≥23.5 mg/mL

Items 1-10 of 39

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  1. Category Chromatin/Epigenetics Remove This Item
  2. Specificity Selective Remove This Item
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Category
  1. Bromodomain 2item
  2. Aurora Kinase 4item
  3. HDAC 9item
  4. Histone Acetyltransferases 2item
  5. Histone Demethylases 1 item
  6. Histone Methyltransferase 4item
  7. HIF 2item
  8. JAK 5item
  9. PARP 3item
  10. Pim 2item
  11. Protein Ser/Thr Phosphatases 3item
  12. Sirtuin 2item
Reversibility
  1. Reversible 1 item
Target
  1. Histone Deacetylases (HDACs) 8item
  2. PI3K 1 item
  3. Aurora Kinases 4item
  4. EZH2 1 item
  5. Bromodomains 1 item
  6. FLT3 1 item
  7. MEK 1 item
  8. DOT1L 1 item
  9. Pim 2item
  10. Sir2-like Family Deacetylases (Sirtuins) 2item
  11. PP1 1 item
  12. PP2A 1 item
  13. Src 1 item
  14. STAT 1 item
  15. Hypoxia Inducible Factors (HIFs) 1 item
  16. JAK 5item
  17. p300 1 item
  18. TNKS 1 item
  19. Topoisomerases 1 item
  20. Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors (HIF-PHIs) 1 item
  21. PARP 2item
  22. phosphatases 1 item
  23. NAT10 1 item
  24. SETD7 1 item
  25. Histone Demethylases 1 item
  26. Protein Arginine Methyltransferases 1 item
  27. PP4 1 item
  28. c-RET 1 item
  29. Protein polybromo-1 1 item
  30. SMARCA4 1 item
  31. SMARCA2 1 item
  32. Lck 1 item
Reported Experiments
  1. Animal Experiments 30item
  2. Cell Experiments 21item
Related Disease
  1. Acute Myeloid Leukemia 2item
  2. Breast Cancer 7item
  3. Cancer 24item
  4. Cervical Cancer 1 item
  5. Colon Cancer 3item
  6. Colon Carcinoma 1 item
  7. Colorectal Cancer 1 item
  8. Diabetes 1 item
  9. Epilepsy 1 item
  10. Glioblastoma 1 item
  11. Glioma 1 item
  12. Hepatic Cancer 1 item
  13. Hepatocellular Carcinoma 1 item
  14. Inflammatory Diseases 1 item
  15. Leukemia 2item
  16. Lung Cancer 1 item
  17. Lymphoma 2item
  18. Melanoma 1 item
  19. Mixed Lineage Leukemia 1 item
  20. Multiple Myeloma 2item
  21. Myelofibrosis 1 item
  22. Non-small Cell Lung Cancer 3item
  23. Ovarian Cancer 3item
  24. Pancreatic Cancer 2item
  25. Prostate Cancer 5item
  26. Renal Cell Carcinoma 1 item
  27. Rheumatoid Arthritis 1 item