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Search results for: 'research area pi3k akt signaling pi3k inhibitors'

Search results for: 'research area pi3k akt signaling pi3k inhibitors'

B1036 MLN4924

5 Citation

Target: NAE|Ubiquitin-activating Enzyme E1|SUMOylation

Summary: NAE inhibitor

≥22.18 mg/mL
B3179 PTC-209

Target: BMI-1

Summary: Bmi-1 inhibitor,cell-permeable and small-molecule

≥24.75 mg/mL
A3875 Tipiracil hydrochloride

Target: Thymidine Phosphorylases

Summary: Thymidine phosphorylase inhibitor

insoluble in DMSO; insoluble in EtOH; ≥13.25 mg/mL
A8370 Axitinib (AG 013736)

1 Citation

Target: VEGFR|PDGFR|c-Kit

Summary: VEGFR1/ c-Kit inhibitor

insoluble in H2O; ≥19.3 mg/mL
A8178 Panobinostat (LBH589)

10 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in H2O; insoluble in EtOH; ≥17.47 mg/mL
A1947 MEK162 (ARRY-162, ARRY-438162)

Target: MEK

Summary: MEK1/2 inhibitor,potent and selective

insoluble in H2O; insoluble in EtOH; insoluble in DMSO
A8633 Concanamycin A

1 Citation

Target: Vacuolar-type ATPase

Summary: V-type (vacuolar) H+-ATPase inhibitor

soluble in DMSO
A3023 P005091

1 Citation

Target: Ubiquitin-specific proteases

Summary: Ubiquitin-specific protease 7 (USP7) inhibitor

insoluble in H2O; insoluble in EtOH; ≥17.4 mg/mL
A2168 Dovitinib (TKI-258, CHIR-258)

2 Citation

Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR

Summary: Multitargeted RTK inhibitor

insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
A8325 Tivantinib (ARQ 197)

2 Citation

Target: MET

Summary: C-Met inhibitor,non-ATP-competitive

≥18.47 mg/mL