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Signaling Pathways

Items 1-10 of 32

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  1. TAK-632
    A8226 TAK-632
    Target: Raf
    Summary: Pan-RAF inhibitor,potent and selective
      ≥27.75 mg/mL
  2. SB 203580
    A8254 SB 203580
     9 Citation
    Target: p38|PKB
    Summary: P38 MAP kinase inhibitor
      insoluble in H2O; ≥18.872 mg/mL
  3. Bumetanide
    A1855 Bumetanide
    Target: Na /K /Cl- Symporters (NKCCs)
    Summary: NKCC cotransporter inhibitor
      insoluble in H2O; ≥36.37 mg/mL
  4. GDC-0879
    A5071 GDC-0879
     1 Citation
    Target: Raf
    Summary: B-Raf inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
  5. SB202190 (FHPI)
    A1632 SB202190 (FHPI)
     5 Citation
    Target: p38
    Summary: P38 MAPK inhibitor
  6. LY2228820
    A5566 LY2228820
     1 Citation
    Target: p38
    Summary: P38 MAP kinase inhibitor
      ≥30.65 mg/mL
  7. Pimasertib (AS-703026)
    A5573 Pimasertib (AS-703026)
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.55 mg/mL
  8. PD318088
    A5707 PD318088
    Target: MEK
    Summary: Allosteric MEK1/2 inhibitor, non-ATP competitive
      ≥28.05 mg/mL
  9. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  10. BIX 02188
    A5803 BIX 02188
    Target: MEK
    Summary: MEK5 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥10.3 mg/mL

Items 1-10 of 32

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