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Signaling Pathways

7 Items

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  1. Pimasertib (AS-703026)
    A5573 Pimasertib (AS-703026)
    Target: MEK
    Summary: MEK1/2 inhibitor
      ≥21.55 mg/mL
  2. PD318088
    A5707 PD318088
    Target: MEK
    Summary: Allosteric MEK1/2 inhibitor, non-ATP competitive
      ≥28.05 mg/mL
  3. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  4. BIX 02188
    A5803 BIX 02188
    Target: MEK
    Summary: MEK5 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; ≥10.3 mg/mL
  5. MEK162 (ARRY-162, ARRY-438162)
    A1947 MEK162 (ARRY-162, ARRY-438162)
    Target: MEK
    Summary: MEK1/2 inhibitor,potent and selective
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO
  6. Refametinib
    B1267 Refametinib
    Target: MEK
    Summary: MEK 1/ MEK 2 inhibitor
      insoluble in H2O; ≥151.8 mg/mL
  7. Trametinib (GSK1120212)
    A3018 Trametinib (GSK1120212)
     7 Citation
    Target: MEK
    Summary: MEK1 and MEK2 inhibitor, potent and selective
      insoluble in H2O; insoluble in EtOH; ≥15.38 mg/mL

7 Items

per page