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Signaling Pathways

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  1. ARP 100
    A4432 ARP 100
     1 Citation
    Target: MMP
    Summary: Selective MMP-2 inhibitor
      ≥36.4 mg/mL
  2. AZ 10417808
    A4416 AZ 10417808
    Target: Caspases
    Summary: Caspase-3 inhibitor,selective non-peptide
      <10.86 mg/mL
  3. BMS 299897
    A4400 BMS 299897
    Summary: γ--secretase inhibitor, potent and orally active
      Soluble in DMSO
  4. JLK 6
    A4403 JLK 6
    Summary: γ-secretase inhibitor
      <22.56 mg/mL
  5. MDL 28170
    A4412 MDL 28170
    Target: Cathepsins|Calpains
    Summary: Calpain and cathepsin B inhibitor, selective
      insoluble in H2O; ≥16.75 mg/mL
  6. PD 150606
    A4413 PD 150606
    Target: Calpains
    Summary: Non-peptide calpain inhibitor
      Soluble in DMSO
  7. SID 26681509
    A4424 SID 26681509
    Target: Cathepsins
    Summary: Human cathepsin L inhibitor,potent and reversible
      <26.98 mg/mL
  8. Sivelestat sodium salt
    A4430 Sivelestat sodium salt
    Target: Elastases
    Summary: Leukocyte elastase inhibitor
      Soluble in DMSO
  9. WAY 170523
    A4442 WAY 170523
    Target: MMP
    Summary: MMP-13 inhibitor,potent and selective
      <61.37 mg/mL
  10. GI 254023X
    A4436 GI 254023X
     2 Citation
    Target: ADAMs
    Summary: Selective inhibitor of ADAM10 metalloprotease
      ≥42.6 mg/mL

Items 1-10 of 80

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Category
  1. Caspase 10item
  2. Aminopeptidase 2item
  3. Calpains 5item
  4. Cathepsin 8item
  5. DPP-4 5item
  6. Elastase 3item
  7. Gamma Secretase 8item
  8. HCV Protease 6item
  9. HSP 13item
  10. HIV Integrase 2item
  11. HIV Protease 5item
  12. MMP 7item
  13. Serine Protease 2item
  14. Thrombin 5item
  15. Other Proteases 2item
Reversibility
  1. Reversible 13item
  2. Irreversible 7item
Target
  1. Caspases 10item
  2. Proteasome 1 item
  3. Cathepsins 11item
  4. MMP 6item
  5. Factor Xa 2item
  6. Thymidylate Synthase 1 item
  7. Aminopeptidases 2item
  8. HSP90 10item
  9. Notch 1 item
  10. thrombin 1 item
  11. Renin 1 item
  12. HIV proteases 1 item
  13. Pepsins 1 item
  14. Calpains 5item
  15. HCV Proteases 3item
  16. Trypsins 1 item
  17. Trypsin 1 item
  18. Chymotrypsin 1 item
  19. Kallikrein 1 item
  20. Trypsinogen 1 item
  21. HIV-1 gp120 1 item
  22. HIV Integrases 1 item
  23. Inward Rectifier Potassium (Kir) Channels 1 item
  24. Papains 1 item
  25. DPP-4 4item
  26. Nonstructural protein 5B (NS5B) 1 item
  27. ADAMs 1 item
  28. Dipeptidyl-peptidase II 1 item
  29. HCV polymerase 2item
  30. Elastases 1 item
  31. NE 1 item
Reported Experiments
  1. Animal Experiments 70item
  2. Cell Experiments 49item
Related Disease
  1. Acute Lung Injury 1 item
  2. Acute Myeloid Leukemia 1 item
  3. Breast Cancer 11item
  4. Cancer 31item
  5. Chronic Lymphocytic Leukemia 1 item
  6. Clear Cell Renal Cell Carcinoma 1 item
  7. Colon Cancer 2item
  8. Diabetes 2item
  9. Glioma 1 item
  10. HCV 3item
  11. Hepatitis C 3item
  12. HIV 1 item
  13. HIV Infections 2item
  14. Inflammatory Diseases 1 item
  15. Lung Cancer 3item
  16. Lymphoma 1 item
  17. Melanoma 7item
  18. Multiple Myeloma 2item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Cancer 2item
  21. Osteoporosis 1 item
  22. Ovarian Cancer 4item
  23. Pancreatic Cancer 3item
  24. Prostate Cancer 3item
  25. Psoriasis 1 item
  26. Renal Cell Carcinoma 1 item
  27. Rheumatoid Arthritis 3item
  28. Squamous Cell Carcinoma 1 item
  29. Type 2 Diabetes 1 item