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Signaling Pathways

Items 1-10 of 14

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  1. Gefitinib (ZD1839)
    A8219 Gefitinib (ZD1839)
     3 Citation
    Target: EGFR
    Summary: Selective EGFR inhibitor
      ≥22.34 mg/mL
  2. PP 1
    A8215 PP 1
    Target: Src|EGFR|JAK|ZAP-70
    Summary: Src family tyrosine kinase inhibitor
  3. Afatinib (BIBW2992)
    A8247 Afatinib (BIBW2992)
     1 Citation
    Target: EGFR
    Summary: Irreversible EGFR/HER2 inhibitor
      ≥24.3 mg/mL
  4. CP-724714
    A2412 CP-724714
    Target: VEGFR|PDGFR|Bcr-Abl|Src|EGFR|c-MET|Insulin Receptors|IRG-1R
    Summary: HER2 inhibitor,potent and selective
      ≥23.5 mg/mL
  5. WZ8040
    A1393 WZ8040
    Target: EGFR
    Summary: EGFR T790M inhibitor,irreversible amd potent
      ≥24.05 mg/mL
  6. AC480 (BMS-599626)
    A2822 AC480 (BMS-599626)
    Target: EGFR
    Summary: HER1/2 inhibitor,selective and efficacious
      ≥28.35 mg/mL
  7. AG-1478
    A8357 AG-1478
    Target: EGFR
    Summary: EGFR inhibitor,potent and selective
      insoluble in H2O; ≥15.8 mg/mL
  8. AZD8931 (Sapitinib)
    A8375 AZD8931 (Sapitinib)
    Target: EGFR|ErbB
    Summary: ErbB inhibitor
      ≥23.7 mg/mL
  9. TAK-285
    A8528 TAK-285
    Target: EGFR|HER2
    Summary: HER2/EGFR(HER1) inhibitor
      ≥27.4 mg/mL
  10. CO-1686 (AVL-301)
    A3320 CO-1686 (AVL-301)
     1 Citation
    Target: EGFR
    Summary: EGFR inhibitor
      ≥27.8 mg/mL

Items 1-10 of 14

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