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Signaling Pathways

Items 1-10 of 234

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  1. SCR7
    A8705 SCR7
     6 Citation
    Summary: DNA ligase IV inhibitor
      insoluble in H2O; ≥16.72 mg/mL
  2. Veliparib dihydrochloride
    A3958 Veliparib dihydrochloride
    Target: PARP
    Summary: PARP-1/PARP-2 inhibitor
      ≥31.7 mg/mL
  3. KD 5170
    A4493 KD 5170
     1 Citation
    Summary: HDAC inhibitor
      ≥21.2 mg/mL
  4. NCH 51
    A4495 NCH 51
    Summary: Histone deacetylase (HDAC) inhibitor
  5. NSC 3852
    A4496 NSC 3852
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC inhibitor
      insoluble in EtOH; insoluble in H2O; ≥7.35 mg/mL
  6. Pyroxamide
    A4497 Pyroxamide
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1 inhibitor
      Soluble in DMSO
  7. TC-H 106
    A4499 TC-H 106
    Summary: HDAC inhibitor
      insoluble in H2O; ≥15.2 mg/mL
  8. Tubacin
    A4501 Tubacin
     3 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC6 inhibitor,potent,selective,reversible,cell-permeable
      insoluble in EtOH; insoluble in H2O; ≥7.19 mg/mL
  9. 4-HQN
    A4524 4-HQN
    Summary: PARP inhibitor
      ≥7.4 mg/mL
  10. BYK 204165
    A4525 BYK 204165
    Summary: PARP-1 inhibitor,potent and selective
      <25.23 mg/mL

Items 1-10 of 234

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  1. Category DNA Damage/DNA Repair Remove This Item
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Category
  1. MTH1 4item
  2. PARP 32item
  3. ATM/ATR 10item
  4. DNA Alkylating 9item
  5. DNA Ligases 3item
  6. DNA Methyltransferase 2item
  7. DNA-PK 8item
  8. DNA Synthesis 52item
  9. HDAC 55item
  10. Nucleoside Antimetabolite/Analogue 13item
  11. Telomerase 5item
  12. Topoisomerase 38item
  13. tankyrase 5item
Specificity
  1. Selective 72item
Reversibility
  1. Reversible 4item
Target
  1. Histone Deacetylases (HDACs) 34item
  2. PI3K 5item
  3. MDM2 1 item
  4. mTOR 1 item
  5. Thymidylate Synthase 2item
  6. STAT 1 item
  7. Estrogen and Related Receptors 1 item
  8. EGFR 1 item
  9. Tankyrases 1 item
  10. DNA-PK 4item
  11. TNKS 1 item
  12. Topoisomerases 11item
  13. ErbB 1 item
  14. DNA Methyltransferases 1 item
  15. PARP 7item
  16. ATM/ATR 6item
  17. AP endonucleases 1 item
  18. HSV 2item
  19. Synthases/Synthetases 1 item
  20. RNA Polymerases 1 item
  21. FoxM1 1 item
  22. O6-methylguanine-DNA-methyl-transferase (MGMT) 1 item
  23. Adenine receptors 1 item
  24. RNA synthesis 1 item
  25. FPTase 1 item
  26. p53 1 item
  27. HDAC 1 item
  28. KDM 1 item
  29. PPAR 1 item
  30. HCV polymerase 1 item
  31. Antibiotic 1 item
  32. DNA Alkylating 2item
  33. telomerase 1 item
  34. Telomerases 1 item
  35. Ribonucleotide Reductases 1 item
  36. PTK 1 item
  37. Adenosine Deaminases 1 item
  38. DNA gyrase 1 item
  39. DNA Ligases 1 item
  40. 5-HT 1 item
  41. PHF 1 item
  42. ATM 2item
  43. MTH1 1 item
Reported Experiments
  1. Animal Experiments 95item
  2. Cell Experiments 79item
Related Disease
  1. Acute Myelogenous Leukemia 2item
  2. Acute Myeloid Leukemia 2item
  3. Bladder Cancer 4item
  4. Breast Cancer 19item
  5. Cancer 68item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Colon Cancer 10item
  8. Colon Carcinoma 1 item
  9. Colorectal Cancer 7item
  10. Dyskinesia 1 item
  11. Epilepsy 1 item
  12. Friedreich's Ataxia 1 item
  13. Glioblastoma 2item
  14. Glioma 2item
  15. HCV 1 item
  16. Hepatic Cancer 1 item
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  18. HIV Infections 1 item
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  22. Lung Cancer 6item
  23. Lymphoma 7item
  24. Melanoma 5item
  25. Multiple Myeloma 3item
  26. Myeloma 2item
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  28. Neuronal Protection 1 item
  29. Non-small Cell Lung Cancer 3item
  30. Ovarian Cancer 8item
  31. Pancreatic Cancer 4item
  32. Prostate Cancer 10item
  33. Renal Cancer 1 item
  34. Renal Cell Carcinoma 2item
  35. Testicular Cancer 1 item