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Signaling Pathways

Signaling Pathways

A3515 JANEX-1

Summary: JAK3 inhibitor

insoluble in EtOH; ≥11.65 mg/mL
A3675 NVP-BSK805

Summary: ATP-competitive JAK2 inhibitor

≥20.95 mg/mL
A3741 Pyridone 6

Target: JAK

Summary: Pan-JAK inhibitor

insoluble in H2O; ≥15.45 mg/mL
A3781 Ruxolitinib phosphate

Summary: JAK1/JAK2 inhibitor

≥20.2 mg/mL
A3794 SB1317

Summary: CDK,JAK and FLT inhibitor

insoluble in H2O; ≥44.87 mg/mL
B1130 GLPG0634

1 Citation

Target: JAK

Summary: JAK1 inhibitor

≥21.3 mg/mL
A3936 WHI-P97

Summary: Janus kinase (JAK)-3 inhibitor

Soluble in DMSO
A3937 XL019

Target: JAK

Summary: JAK2 inhibitor,potent and selective

insoluble in EtOH; insoluble in H2O; ≥11.125 mg/mL
A3012 Ruxolitinib (INCB018424)

4 Citation

Target: JAK

Summary: JAK inhibitor

insoluble in H2O; ≥15.32 mg/mL
A4135 Tofacitinib (CP-690550) Citrate

2 Citation

Target: JAK

Summary: Potent JAK inhibitor

≥25.22 mg/mL