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Signaling Pathways

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  1. Nilotinib(AMN-107)
    A8232 Nilotinib(AMN-107)
     1 Citation
    Target: Bcr-Abl
    Summary: Bcr-Abl kinase inhibitor,selective
      ≥26.5 mg/mL
  2. SB 431542
    A8249 SB 431542
     2 Citation
    Summary: ALK inhibitor
  3. Bosutinib (SKI-606)
    A2149 Bosutinib (SKI-606)
     1 Citation
    Target: Bcr-Abl|Src
    Summary: Potent Abl/Src kinases
      ≥26.5 mg/mL
  4. Enzastaurin (LY317615)
    A1670 Enzastaurin (LY317615)
     2 Citation
    Target: PKC
    Summary: PKC beta inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥8.59 mg/mL
  5. Zoledronic Acid
    A1352 Zoledronic Acid
    Target: Farnesyl Diphosphate Synthases
    Summary: Potent nitrogen-containing bisphosphonates
      insoluble in DMSO; insoluble in H2O; insoluble in EtOH
  6. LY2157299
    A8348 LY2157299
     2 Citation
    Summary: TGF-βR1 inhibitor,potent and selective
      insoluble in H2O; ≥18.45 mg/mL
  7. PF-562271 HCl
    A8345 PF-562271 HCl
    Target: FAK|Pyk2
    Summary: FAK/Pyk2 inhibitor
      ≥26.35 mg/mL
  8. Go 6976
    A8341 Go 6976
    Target: PKC
    Summary: PKCα/PKCβ1 inhibitor
      ≥15.77 mg/mL
  9. DCC-2036 (Rebastinib)
    B1404 DCC-2036 (Rebastinib)
    Target: FLT3|Bcr-Abl|Tie-2|KDR
    Summary: Bcr-Abl inhibitor
      ≥27.7 mg/mL
  10. RKI-1447
    A3771 RKI-1447
    Target: ROCK
    Summary: Potent ROCK1/ROCK2 inhibitor
      insoluble in H2O; ≥16.3 mg/mL

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