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Signaling Pathways

Items 1-10 of 659

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  1. Spadin
    B6071 Spadin
    Summary: TREK-1 channel inhibitor
      Soluble to 2 mg/mL
  2. RBC8
    B4884 RBC8
    Summary: Ral GTPase inhibitor
      Soluble in DMSO
  3. PF-03716556
    A3968 PF-03716556
    Summary: Acid pump antagonist,potent and selective
      Soluble in DMSO
  4. Flumazenil
    A2917 Flumazenil
    Target: GABAA Receptors
    Summary: Benzodiazepine antagonist
      insoluble in H2O; insoluble in EtOH; ≥30.38 mg/mL
  5. Cilnidipine
    A1447 Cilnidipine
    Summary: Blocker of Dual L- and N-type calcium channel
      ≥24.63 mg/mL
  6. Etomidate
    A1958 Etomidate
    Target: GABAA Receptors
    Summary: General anesthetic with GABA modulatory and GABA-mimetic actions
      insoluble in H2O; ≥12.212 mg/mL
  7. TRAM-34
    A1888 TRAM-34
    Target: Calcium-Activated Potassium (KCa) Channels
    Summary: KCa3.1 blocker,potent and highly selective
      insoluble in H2O; insoluble in EtOH; ≥17.25 mg/mL
  8. Bumetanide
    A1855 Bumetanide
    Target: Na /K /Cl- Symporters (NKCCs)
    Summary: NKCC cotransporter inhibitor
      insoluble in H2O; ≥36.37 mg/mL
  9. Ivermectin
    A2813 Ivermectin
    Summary: NAChR/purinergic P2X4 receptor modulator
      ≥43.75 mg/mL
  10. Ivacaftor (VX-770)
    A5047 Ivacaftor (VX-770)
     1 Citation
    Summary: Potent CFTR potentiator
      insoluble in H2O; ≥19.6 mg/mL

Items 1-10 of 659

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Category
  1. AMPAR 43item
  2. ATPase 38item
  3. Calcium Channel 78item
  4. Cannabinoid Transporters 6item
  5. CFTR 10item
  6. Chloride Channels 13item
  7. GABA Receptor 89item
  8. Glucose Transporters 2item
  9. Glutamate (EAAT) Transporters 17item
  10. Glycine Receptors 2item
  11. GlyT1 5item
  12. GTPase 6item
  13. Kv1.3 1 item
  14. ICB 1 item
  15. MCT2 2item
  16. Monoamine transporter 1 item
  17. Monocarboxylate Transporters 1 item
  18. Multidrug Transporters 4item
  19. Na+/Ca2+ Exchanger 7item
  20. NKCC 3item
  21. NMDA Receptor 72item
  22. Nucleoside Transporters 3item
  23. Pannexin-1 2item
  24. P2X purinergic receptor 29item
  25. P-gp 9item
  26. Proton Pump 11item
  27. Potassium Channel 76item
  28. Sodium Channel 44item
  29. TRP Channel 41item
  30. TRPV1 10item
  31. URAT1 1 item
  32. Other Channel Modulators 8item
  33. MCT 3item
  34. Kainate Receptors 12item
  35. Ionophore 3item
  36. sodium-hydrogen exchanger 3item
  37. nAChR 1 item
  38. iGluR 2item
  39. Chloride Channel 1 item
Specificity
  1. Selective 57item
Reversibility
  1. Reversible 5item
Target
  1. Gap Junctions 1 item
  2. Myosin II ATPases 1 item
  3. Voltage-gated Potassium (KV) Channels 2item
  4. P-glycoprotein (P-gp) 4item
  5. GABAB Receptors 2item
  6. Voltage-gated Sodium (NaV) Channels 10item
  7. NMDA Receptors 4item
  8. CFTR 4item
  9. Cytochrome P450 (CYP450) 2item
  10. DNA Methyltransferases 1 item
  11. Epac 1 item
  12. Ca2 /calmodulin-dependent protein kinases (CaMKs) 2item
  13. Calcium ionophores 1 item
  14. Voltage-gated Calcium Channels (CaV) 10item
  15. GTPases 1 item
  16. Monocarboxylate transporters (MCTs) 2item
  17. Myosin light chain kinases (MLCKs) 1 item
  18. CaM-KK 1 item
  19. AMPA 1 item
  20. Na /H Exchangers (NHEs) 1 item
  21. Delayed rectifier outward potassium current (IKr) 1 item
  22. P2X Receptors 1 item
  23. Carbonic Anhydrases 1 item
  24. Calcium-activated chloride channels (CaCC) 1 item
  25. GPR35 1 item
  26. Urokinases 1 item
  27. Synthases/Synthetases 1 item
  28. Na /K ATPases 2item
  29. Na /K /Cl- Symporters (NKCCs) 2item
  30. GABAA Receptors 3item
  31. TRP Channel 2item
  32. Ionophores 1 item
  33. Calcium-Activated Potassium (KCa) Channels 2item
  34. Proton Pump 1 item
  35. cAMP 1 item
  36. Sulfonylurea receptors 1 item
  37. Inward Rectifier Potassium (Kir) Channels 3item
  38. Na /Ca2 Exchangers (NCXs) 1 item
  39. Myosin 1 item
  40. 5-HT receptors 1 item
  41. sodium channel 2item
  42. TRPV 1 item
  43. NTPDases 1 item
  44. Calmodulins 1 item
  45. TRPA 1 item
  46. F1 Fo-ATPase 1 item
  47. AMPA Receptors 1 item
  48. mitochondrial pyruvate carrier (MPC) 1 item
  49. Protein Tyrosine Phosphatases 1 item
  50. alkaline phosphatases 1 item
  51. ATPases 1 item
  52. benzodiazepine receptor 1 item
  53. glutamate release 1 item
  54. NHE 1 item
  55. GABAA receptor 1 item
  56. Ca2 -ATPases 1 item
Reported Experiments
  1. Animal Experiments 73item
  2. Cell Experiments 66item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Anesthesia 2item
  3. Breast Cancer 1 item
  4. Cancer 10item
  5. Epilepsy 3item
  6. Glioma 1 item
  7. Heart Failure 3item
  8. Leukemia 1 item
  9. Lymphoma 2item
  10. Non-small Cell Lung Cancer 2item
  11. Non-small Cell Lung Carcinoma 2item
  12. Ovarian Cancer 1 item
  13. Type 2 Diabetes 5item