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Signaling Pathways

Items 1-10 of 69

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  1. GKT137831
    B4763 GKT137831
     1 Citation
    Target: NADPH Oxidases
    Summary: dual NADPH oxidase Nox1/Nox4 inhibitor
      ≥39.5 mg/mL
  2. Adapalene
    A1267 Adapalene
    Target: RARs
    Summary: RARβ and RARγ agonist
      insoluble in H2O; insoluble in EtOH; ≥10.31 mg/mL
  3. Acitretin
    A2415 Acitretin
    Target: RARs
    Summary: Metabolite of etretinate
      insoluble in EtOH; insoluble in H2O; ≥16.32 mg/mL
  4. SC 144
    A2173 SC 144
     1 Citation
    Target: Glycoproteins
    Summary: Gp130 inhibitor
      insoluble in EtOH; insoluble in H2O; ≥16.1 mg/mL
  5. Verteporfin
    A8327 Verteporfin
    Target: YAP
    Summary: Photosensitizer used in photodynamic therapy
      insoluble in EtOH; insoluble in H2O; ≥18.3 mg/mL
  6. Allopurinol
    A8360 Allopurinol
    Target: Xanthine oxidoreductases
    Summary: Xanthine oxidase inhibitor
      insoluble in H2O; insoluble in EtOH; ≥5.15 mg/mL
  7. Bexarotene
    A8380 Bexarotene
    Target: Retinoid X receptors (RXR)
    Summary: Retinoid Receptor agonist
      insoluble in H2O; ≥10.35 mg/mL
  8. Potassium Canrenoate
    A8506 Potassium Canrenoate
    Target: Aldosterone receptor
    Summary: Aldosterone antagonist
      insoluble in EtOH; insoluble in DMSO; ≥117.4 mg/mL
  9. Terfenadine
    A8534 Terfenadine
    Target: Voltage-gated Potassium (KV) Channels|Histamine H1 Receptors|Inward Rectifier Potassium (Kir) Channels
    Summary: Histamine H1-receptor antagonist
      insoluble in H2O; ≥18 mg/mL
  10. Thioridazine HCl
    A8537 Thioridazine HCl
    Target: Cytochrome P450 (CYP450)|D1 and D5 Receptors|D2 Receptors|D3 Receptors|D4 Receptors
    Summary: Calcium channel protein inhibitor

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