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Signaling Pathways

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  1. BMS-345541(free base)
    B4655 BMS-345541(free base)
    Summary: IKK-1/IKK-2 inhibitor,potent and selective
      insoluble in H2O; ≥70 mg/mL
  2. SC-514
    B1585 SC-514
    Summary: ATP-competitive IKK-2 inhibitor, orally active
      insoluble in EtOH; insoluble in H2O; ≥50.4 mg/mL
  3. IKK-16 (IKK Inhibitor VII)
    B1586 IKK-16 (IKK Inhibitor VII)
     1 Citation
    Summary: Selective IκB kinase inhibitor
      ≥23.05 mg/mL
  4. Resiquimod (R-848)
    B1054 Resiquimod (R-848)
     2 Citation
    Target: Toll-like receptors (TLRs)
    Summary: Immune response modifier
  5. Curcumin
    A3335 Curcumin
     1 Citation
    Target: Histone Deacetylases (HDACs)|Nrf2|Histone Acetyltransferases (HATs)|Tyrosinases
    Summary: Tyrosinase inhibitor
      ≥36.8 mg/mL
  6. Emodin
    A3392 Emodin
    Target: CK2
    Summary: Naturally occurring anthraquinone,antiproliferative
      ≥27 mg/mL
  7. IKK-2 inhibitor VIII
    A3485 IKK-2 inhibitor VIII
    Summary: IKK-2 inhibitor,potent and selective
      Soluble in DMSO
  8. TAK-242
    A3850 TAK-242
     7 Citation
    Target: Toll-like receptors (TLRs)|NO Donors / Precursors|IL Receptors
    Summary: TLR 4 signaling inhibitor
  9. Mesalamine
    B1969 Mesalamine
    Summary: IKK inhibitor
      insoluble in EtOH; insoluble in H2O; ≥7.65 mg/mL
  10. Suprofen
    B2133 Suprofen
    Target: COX
    Summary: dual COX-1/COX-2 inhibitor
      insoluble in H2O; ≥82.8 mg/mL

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