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Signaling Pathways

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  1. Anacardic acid
    A4488 Anacardic acid
    Target: Histone Acetyltransferases (HATs)
    Summary: HAT inhibitor
      insoluble in H2O; ≥17.45 mg/mL
  2. TC-A 2317 hydrochloride
    A4489 TC-A 2317 hydrochloride
    Target: Aurora Kinases
    Summary: Aurora kinase A inhibitor,potent and selective
      <39.29 mg/mL
  3. MK-8745
    A8807 MK-8745
    Target: Aurora Kinases
    Summary: Aurora A inhibitor,potent and selective
      ≥21.6 mg/mL
  4. Reversine
    A3760 Reversine
    Target: Aurora Kinases
    Summary: A3 adenosine receptor antagonist,ARK-1/-2/-3 inhibitor
      insoluble in H2O; ≥19.65 mg/mL
  5. SCH-1473759
    A3804 SCH-1473759
    Summary: Aurora A/B inhibitor
      Soluble in DMSO
  6. XL228
    A3939 XL228
    Summary: IGF1R/AURORA /FGFR1-3/ABL/SRC family kinases inhibitor
      ≥21.9 mg/mL
  7. MLN8237 (Alisertib)
    A4110 MLN8237 (Alisertib)
     6 Citation
    Summary: Aurora A Kinase inhibitor, Potent and selective
      ≥25.95 mg/mL
  8. VX-680 (MK-0457,Tozasertib)
    A4111 VX-680 (MK-0457,Tozasertib)
    Target: Aurora Kinases
    Summary: Aurora kinase inhibitor
      ≥23.25 mg/mL
  9. Barasertib (AZD1152-HQPA)
    A4112 Barasertib (AZD1152-HQPA)
     3 Citation
    Target: Aurora Kinases
    Summary: Aurora Kinase B inhibitor, Potent and selective
      ≥25.4 mg/mL
  10. ZM 447439
    A4113 ZM 447439
    Target: Aurora Kinases|MEK|Src|Lck
    Summary: Aurora Kinase inhibitor,potent and selective
      ≥25.7 mg/mL

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