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Signaling Pathways

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  1. AZD1208
    A3962 AZD1208
    Target: Pim
    Summary: PIM kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.95 mg/mL
  2. I-CBP 112
    A4490 I-CBP 112
    Target: CREBBP|EP300
    Summary: CBP/EP300 bromodomain inhibitor
      ≥49.6 mg/mL
  3. Nilotinib(AMN-107)
    A8232 Nilotinib(AMN-107)
     1 Citation
    Target: Bcr-Abl
    Summary: Bcr-Abl kinase inhibitor,selective
      ≥26.5 mg/mL
  4. SNS-032 (BMS-387032)
    A1980 SNS-032 (BMS-387032)
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK inhibitor
      insoluble in H2O; ≥19.05 mg/mL
  5. 17-DMAG (Alvespimycin) HCl
    A2213 17-DMAG (Alvespimycin) HCl
     1 Citation
    Target: HSP90
    Summary: Hsp90 inhibitor
      ≥26.2 mg/mL
  6. Quizartinib (AC220)
    A5793 Quizartinib (AC220)
    Target: FLT3
    Summary: FLT3 inhibitor,potent and selective
      ≥28.03 mg/mL
  7. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  8. Crenolanib (CP-868596)
    A8307 Crenolanib (CP-868596)
     1 Citation
    Target: FLT3|PDGFR
    Summary: PDGFR-β inhibitor,potent and selective
      ≥22.2 mg/mL
  9. PD 0332991 (Palbociclib) HCl
    A8316 PD 0332991 (Palbociclib) HCl
     5 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥14.48 mg/mL
  10. Palbociclib (PD0332991) Isethionate
    A8335 Palbociclib (PD0332991) Isethionate
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥28.7 mg/mL

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