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Signaling Pathways

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  1. AZD1208
    A3962 AZD1208
    Target: Pim
    Summary: PIM kinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥18.95 mg/mL
  2. Nilotinib(AMN-107)
    A8232 Nilotinib(AMN-107)
     1 Citation
    Target: Bcr-Abl
    Summary: Bcr-Abl kinase inhibitor,selective
      ≥26.5 mg/mL
  3. SNS-032 (BMS-387032)
    A1980 SNS-032 (BMS-387032)
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK inhibitor
      insoluble in H2O; ≥19.05 mg/mL
  4. Quizartinib (AC220)
    A5793 Quizartinib (AC220)
    Target: FLT3
    Summary: FLT3 inhibitor,potent and selective
      ≥28.03 mg/mL
  5. BIX 02189
    A5801 BIX 02189
    Target: MEK|ERK
    Summary: Selective MEK5 inhibitor
      ≥22.05 mg/mL
  6. PD 0332991 (Palbociclib) HCl
    A8316 PD 0332991 (Palbociclib) HCl
     5 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥14.48 mg/mL
  7. Thioridazine HCl
    A8537 Thioridazine HCl
    Target: Cytochrome P450 (CYP450)|D1 and D5 Receptors|D2 Receptors|D3 Receptors|D4 Receptors
    Summary: Calcium channel protein inhibitor
  8. Lomustine
    B1963 Lomustine
     1 Citation
    Target: RNA synthesis
    Summary: Antineoplastic drug
      insoluble in H2O; ≥23.41 mg/mL
  9. LY2801653
    A3573 LY2801653
    Target: MET
    Summary: MET inhibitor
      ≥27.65 mg/mL
  10. OTX-015
    A3692 OTX-015
     3 Citation
    Target: Bromodomains
    Summary: BRD inhibitor
      ≥24.6 mg/mL

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