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Signaling Pathways

5 Items

per page
  1. GNF-5837
    A8303 GNF-5837
    Target: Trk Receptors
    Summary: Pan-Trk inhibitor
      insoluble in EtOH; insoluble in H2O; ≥17 mg/mL
  2. Amitriptyline HCl
    B2231 Amitriptyline HCl
    Target: Trk Receptors|5-HT2 Receptors|Norepinephrine transporter|5-HT Transporters
    Summary: Serotonin /norepinephrine receptor/5-HT4/5-HT2 inhibitor
      ≥15.69 mg/mL
  3. LY2784544
    A4147 LY2784544
    Target: Aurora Kinases|FLT3|VEGFR|FGFR|Trk Receptors|JAK|ALK|TYK2|MUSK|MAP3K
    Summary: JAK2 inhibitor,highly potent and selective
      ≥23.5 mg/mL
  4. Altiratinib
    B5832 Altiratinib
     1 Citation
    Target: FLT3|VEGFR|Trk Receptors|c-MET|Tie-2
    Summary: c-MET/TIE-2/VEGFR inhibitor
      ≥21.55 mg/mL
  5. Entrectinib
    B5859 Entrectinib
    Target: Trk Receptors|ALK|ROS1
    Summary: Orally active inhibitor of ALK kinase
      ≥28.05 mg/mL

5 Items

per page