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Signaling Pathways

Items 1-10 of 15

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  1. Etoposide
    A1971 Etoposide
     4 Citation
    Target: Topoisomerases
    Summary: Topo II inhibitor
      ≥29.45 mg/mL
  2. XL147
    A5112 XL147
    Target: PI3K
    Summary: PI3K inhibitor,selective and reversible
      ≥22.45 mg/mL
  3. AZD-3463
    A8620 AZD-3463
     3 Citation
    Target: ALK|Insulin-like growth factors (IGFs)
    Summary: ALK/IGF1R inhibitor
      insoluble in H2O; insoluble in EtOH; ≥11.22 mg/mL
  4. LEE011
    A8641 LEE011
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥10.88 mg/mL
  5. LCL161
    A3541 LCL161
     1 Citation
    Target: Inhibitor of apoptosis proteins (IAP)
    Summary: Antagonist of IAPs inhibitor
      ≥25.05 mg/mL
  6. GSK1324726A
    B1013 GSK1324726A
    Target: Bromodomains
    Summary: BET proteins inhibitor
  7. Romidepsin (FK228, depsipeptide)
    A8173 Romidepsin (FK228, depsipeptide)
     7 Citation
    Target: Histone Deacetylases (HDACs)
    Summary: HDAC1/HDAC2 inhibitor, potent and selective
      ≥27.04 mg/mL
  8. Talabostat mesylate
    B3941 Talabostat mesylate
     2 Citation
    Target: DPP-4
    Summary: orally active, specific inhibitor of DPP4
      ≥11.45 mg/mL
  9. Lactacystin (Synthetic)
    A2583 Lactacystin (Synthetic)
     1 Citation
    Target: Proteasome
    Summary: Proteasome inhibitor
      Soluble in H2O
  10. Ketoconazole
    A4316 Ketoconazole
    Target: Cytochrome P450 (CYP450)
    Summary: Inhibitor of cyclosporine oxidase and testosterone 6 beta-hydroxylase
      ≥23.4 mg/mL

Items 1-10 of 15

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