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Signaling Pathways

Signaling Pathways

A8496 Paliperidone

Target: 5-HT2 Receptors|D2 Receptors|D3 Receptors|5-HT1 Receptors|Histamine H1 Receptors

Summary: Dopamine receptor antagonist

insoluble in H2O; insoluble in EtOH; ≥10.662 mg/mL
B2235 Clozapine

Target: 5-HT2 Receptors|D1 and D5 Receptors|D2 Receptors|D3 Receptors|5-HT1 Receptors|D4 Receptors

Summary: 5-HT receptor antagonist

insoluble in H2O; ≥14.95 mg/mL
B2240 Olanzapine

Target: 5-HT2 Receptors|D2 Receptors

Summary: Antagonist of 5-HT2A and dopamine D2 receptors

insoluble in H2O; ≥15.6 mg/mL
B1001 Loxapine

1 Citation

Target: 5-HT2 Receptors

Summary: 5-HT receptor antagonist

Soluble in DMSO
B1490 Quetiapine Fumarate

1 Citation

Target: 5-HT2 Receptors|D1 and D5 Receptors|D2 Receptors|D3 Receptors|5-HT1 Receptors|5-HT7 Receptors

Summary: Dopamine receptor antagonist

insoluble in H2O; insoluble in EtOH; ≥11.03 mg/mL
B1477 Lurasidone HCl

Target: 5-HT2 Receptors|D2 Receptors|5-HT1 Receptors|5-HT7 Receptors

Summary: Dopamine D2/5-HT2A/5-HT7/5-HT1A inhibitor

insoluble in H2O; insoluble in EtOH; ≥11.11 mg/mL
B1206 Pizotifen

Target: 5-HT2 Receptors

Summary: Highly selective 5-HT receptor blocking agent

insoluble in H2O; ≥14.77 mg/mL
B2007 Pizotifen Malate

Target: 5-HT2 Receptors|D2 Receptors

Summary: 5-HT receptor antagonist

≥21.48 mg/mL
B2231 Amitriptyline HCl

Target: Trk Receptors|5-HT2 Receptors|Norepinephrine transporter|5-HT Transporters

Summary: Serotonin /norepinephrine receptor/5-HT4/5-HT2 inhibitor

≥15.69 mg/mL
B2248 Ketanserin

Target: 5-HT2 Receptors

Summary: specific 5-HT2A serotonin receptor antagonist

≥39.5 mg/mL