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Signaling Pathways

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  1. THZ2
    A8717 THZ2
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK7 inhibitor
      ≥28.3 mg/mL
  2. SNS-032 (BMS-387032)
    A1980 SNS-032 (BMS-387032)
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK inhibitor
      insoluble in H2O; ≥19.05 mg/mL
  3. AT7519
    A5719 AT7519
    Target: Cyclin-Dependent Kinases
    Summary: Multi-CDK inhibitor
  4. PD 0332991 (Palbociclib) HCl
    A8316 PD 0332991 (Palbociclib) HCl
     5 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK4/6 inhibitor,highly selective
      ≥14.48 mg/mL
  5. AZD-5438
    A8326 AZD-5438
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK1/2/9 inhibitor
      insoluble in H2O; ≥18.55 mg/mL
  6. PHA-848125
    A8501 PHA-848125
    Target: Cyclin-Dependent Kinases
    Summary: CDK inhibitor,potent and ATP-competitive
      ≥23.05 mg/mL
  7. Dinaciclib (SCH727965)
    A8412 Dinaciclib (SCH727965)
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: Potent CDK inhibitor
  8. Purvalanol B
    A8565 Purvalanol B
     1 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/CDK2/CDK4 inhibitor
      ≥21.65 mg/mL
  9. A-674563
    A8616 A-674563
    Target: Cyclin-Dependent Kinases|Akt|GSK-3|ERK|PKC|PKA|RSK
    Summary: Akt1/PKA/CDK2 inhibitor,potent and selective
      insoluble in EtOH; ≥23.8 mg/mL
  10. R547
    A8642 R547
     2 Citation
    Target: Cyclin-Dependent Kinases
    Summary: CDK1/2/4 inhibitor,ATP-competitive
      Soluble in DMSO

Items 1-10 of 21

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