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Signaling Pathways

9 Items

per page
  1. Regorafenib
    A8236 Regorafenib
     4 Citation
    Target: Raf|VEGFR|PDGFR|c-Kit|RET
    Summary: Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1
      ≥25.04 mg/mL
  2. Imatinib Mesylate (STI571)
    A1805 Imatinib Mesylate (STI571)
    Target: PDGFR|c-Kit|Bcr-Abl
    Summary: Abl/c-kit/PDGFR inhibitor
      ≥29.5 mg/mL
  3. Dovitinib (TKI-258, CHIR-258)
    A2168 Dovitinib (TKI-258, CHIR-258)
     2 Citation
    Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Multitargeted RTK inhibitor
      insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL
  4. Telatinib (BAY 57-9352)
    A8550 Telatinib (BAY 57-9352)
    Target: VEGFR|PDGFR|c-Kit
    Summary: VEGFR-2/-3,PDGFR-β and c-Kit inhibitor
      insoluble in H2O; insoluble in EtOH; ≥20.5 mg/mL
  5. Regorafenib hydrochloride
    A3750 Regorafenib hydrochloride
    Target: Raf|VEGFR|PDGFR|c-Kit|c-RET
    Summary: Tyrosine kinase inhibitor
      ≥25.95 mg/mL
  6. Pazopanib (GW-786034)
    A3022 Pazopanib (GW-786034)
    Target: CSF-1R|VEGFR|PDGFR|c-Kit|FGFR
    Summary: VEGFR/PDGFR/FGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥10.95 mg/mL
  7. AZD2932
    B5835 AZD2932
    Target: FLT3|VEGFR|PDGFR|c-Kit
    Summary: inhibitor of VEGFR-2, PDGFRβ, Flt-3, and c-Kit
      Soluble in DMSO
  8. Dovitinib (TKI258) Lactate
    B5953 Dovitinib (TKI258) Lactate
    Target: CSF-1R|FLT3|VEGFR|PDGFR|c-Kit|FGFR
    Summary: Oral tyrosine kinase inhibitor (TKI) against FGFR1–3, VEGFR1–3, and platelet-derived growth factor receptor (PDGFR).
      insoluble in EtOH; ≥10.62 mg/mL
  9. Dasatinib Monohydrate
    B5954 Dasatinib Monohydrate
    Target: PDGFR|c-Kit|Bcr-Abl|Src
    Summary: Inhibitor of ABL, SRC, KIT, PDGFR, and other tyrosine kinases.
      ≥25.3 mg/mL

9 Items

per page