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Signaling Pathways

Signaling Pathways

A4465 MIM1

1 Citation

Target: Mcl-1

Summary: Mcl-1 Inhibitor

insoluble in EtOH; insoluble in H2O; ≥12.15 mg/mL
B1080 Marinopyrrole A

Target: Mcl-1

Summary: Selective Mcl-1 inhibitor

Soluble in DMSO
A4234 TW-37

1 Citation

Target: Bcl-2|Bcl-xl|Mcl-1

Summary: Bcl-2 inhibitor, inhibits Bcl-2,Bcl-XL and Mcl-1

insoluble in H2O; ≥19.75 mg/mL
A4200 Apogossypolone (ApoG2)

2 Citation

Target: Bcl-2|Bcl-xl|Mcl-1

Summary: Bcl-2 inhibitor,nonpeptidic small molecule

≥24.55 mg/mL
A4199 Sabutoclax

2 Citation

Target: Bcl-2|Mcl-1|Bfl-1

Summary: pan-Bcl-2 inhibitor

insoluble in H2O; ≥205.6 mg/mL