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Signaling Pathways

Items 1-10 of 22

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  1. Cercosporamide
    A4511 Cercosporamide
    Target: JAK|MNK
    Summary: Mnk2 and JAK3 inhibitor
      soluble in DMSO
  2. Cucurbitacin I
    A4512 Cucurbitacin I
    Target: STAT|JAK
    Summary: STAT3/JAK2 signaling inhibitor
      ≥22.45 mg/mL
  3. PP 1
    A8215 PP 1
    Target: Src|EGFR|JAK|ZAP-70
    Summary: Src family tyrosine kinase inhibitor
  4. Pyridone 6
    A3741 Pyridone 6
    Target: JAK
    Summary: Pan-JAK inhibitor
      insoluble in H2O; ≥15.45 mg/mL
  5. GLPG0634
    B1130 GLPG0634
     1 Citation
    Target: JAK
    Summary: JAK1 inhibitor
      ≥21.3 mg/mL
  6. XL019
    A3937 XL019
    Target: JAK
    Summary: JAK2 inhibitor,potent and selective
      insoluble in EtOH; insoluble in H2O; ≥11.125 mg/mL
  7. Ruxolitinib (INCB018424)
    A3012 Ruxolitinib (INCB018424)
     4 Citation
    Target: JAK
    Summary: JAK inhibitor
      insoluble in H2O; ≥15.32 mg/mL
  8. Tofacitinib (CP-690550) Citrate
    A4135 Tofacitinib (CP-690550) Citrate
     2 Citation
    Target: JAK
    Summary: Potent JAK inhibitor
      ≥25.22 mg/mL
  9. TG101348 (SAR302503)
    A4136 TG101348 (SAR302503)
     2 Citation
    Target: FLT3|JAK|c-RET
    Summary: JAK-2 inhibitor,potent and selective
      ≥26.23 mg/mL
  10. AZD1480
    A4137 AZD1480
    Target: JAK
    Summary: JAK2 inhibitor,ATP-competitive and novel
      insoluble in H2O; ≥93.8 mg/mL

Items 1-10 of 22

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