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Items 1-10 of 11

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  1. Zonisamide
    A5354 Zonisamide
    Target: Voltage-gated Sodium (NaV) Channels|Voltage-gated Calcium Channels (CaV)|Carbonic Anhydrases|Calcium-Activated Potassium (KCa) Channels
    Summary: Antiepileptic with anticonvulsant and mechanistic effect
      insoluble in H2O; ≥8.35 mg/mL
  2. Riluzole
    A8513 Riluzole
    Target: Voltage-gated Sodium (NaV) Channels|glutamate release
    Summary: Sodium channel protein inhibitor
      ≥23.4 mg/mL
  3. A-803467
    B2277 A-803467
    Target: Voltage-gated Sodium (NaV) Channels
    Summary: NaV1.8 channel blocker,potent and selective
      insoluble in H2O; ≥13.95 mg/mL
  4. Flecainide acetate
    A3418 Flecainide acetate
    Target: Voltage-gated Sodium (NaV) Channels
    Summary: Antiarrhythmic drug
      ≥23.7 mg/mL
  5. Proparacaine HCl
    B2274 Proparacaine HCl
    Target: Voltage-gated Sodium (NaV) Channels
    Summary: voltage-gated sodium channels antagonist
      insoluble in EtOH; ≥14.9 mg/mL
  6. Phenytoin sodium
    B2272 Phenytoin sodium
    Target: Voltage-gated Sodium (NaV) Channels
    Summary: Sodium channel stabilizer
      insoluble in H2O; insoluble in EtOH; ≥11.55 mg/mL
  7. Bupivacaine HCl
    B1420 Bupivacaine HCl
    Target: Voltage-gated Sodium (NaV) Channels
    Summary: Anaesthetic drug
      ≥10.25 mg/mL
  8. Amiloride HCl dihydrate
    B2268 Amiloride HCl dihydrate
    Target: Voltage-gated Sodium (NaV) Channels|Voltage-gated Calcium Channels (CaV)|Urokinases
    Summary: potent epithelial sodium channel (ENaC) blocker
      insoluble in EtOH; insoluble in H2O; ≥14.05 mg/mL
  9. GX-674
    A8718 GX-674
    Target: Voltage-gated Sodium (NaV) Channels
    Summary: Nav1.7 antagonist
      Soluble in DMSO
  10. Quinidine
    B7590 Quinidine
    Target: Voltage-gated Sodium (NaV) Channels|Cytochrome P450 (CYP450)
    Summary: reduces both Na+ and K+ channel currents

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