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Microtubule/Tubulin

Microtubule is the cylindrical and filamentous structure that required for cell shape, migration, cilia and flagella mobility etc. Tubulin is the major component of microtubules.

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  1. Myoseverin
    B6076 Myoseverin
    Summary: microtubule-binding molecule
      Soluble in DMSO
  2. Ferulenol
    C3889 Ferulenol
    Summary: antimycobacterial activity and stimulates tubulin polymerization
      Soluble in DMSO
  3. ELR510444
    B5870 ELR510444
    Summary: Novel microtubule disruptor
      insoluble in H2O; insoluble in EtOH; ≥11.9 mg/mL
  4. Cevipabulin
    B5922 Cevipabulin
    Summary: Anti-microtubule agent
      Soluble in DMSO
  5. Mebendazole
    C4087 Mebendazole
    Summary: broad-spectrum anthelmintic that inhibits intestinal microtubule synthesis
      insoluble in H2O; insoluble in EtOH; ≥13 mg/mL
  6. Phomopsin A
    C4226 Phomopsin A
    Summary: cyclic hexapeptide mycotoxin that binds β-tubulin
      Soluble in DMSO
  7. INH6
    B4757 INH6
    Summary: Hec1/Nek2 inhibitor, potent
      ≥32.2 mg/mL
  8. MPC 6827 hydrochloride
    B7788 MPC 6827 hydrochloride
    Summary: Potent microtubule inhibitor
      ≥10.55 mg/mL
  9. TAI-1
    B4892 TAI-1
    Target: Hec1
    Summary: Hec1 inhibitor, potent, first-in-class
      ≥43.2 mg/mL
  10. Eribulin mesylate
    B3386 Eribulin mesylate
    Summary: synthetic analogue of halichondrin B
      Soluble in DMSO

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