Topoisomerase
Topoisomerase are enzymes that regulate the overwinding or underwinding of DNA.
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A3355 Deferasirox Fe3+ chelateSummary: Oral iron chelator
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A3372 DOXO-EMCHSummary: Prodrug of doxorubicin
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A3434 Genz-644282Summary: Non-camptothecin inhibitor of topoisomerase I
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A3872 TH-302Summary: Hypoxia-activated prodrug,inhibits H460/HT29 cell growth
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A3924 VoreloxinSummary: Topo II inhibitor
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A3925 Voreloxin HydrochlorideSummary: Antineoplastic naphthyridine analogue
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A3123 4'-DemethylepipodophyllotoxinSummary: Anti-cancer drug
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B2296 Topotecan HClSummary: Topoisomerase 1 inhibitor
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B2293 Irinotecan HCl TrihydrateTarget: TopoisomerasesSummary: Topoisomerase 1 inhibitor
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B2292 FlumequineSummary: DNA topoisomerase II inhibitor,synthetic chemotherapeutic antibiotic