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Leukotriene Receptor

Leukotrienes receptors are divided into two types, BLT receptors and CycLT receptors. BLT receptors mediate chemoattraction. CysLT receptors mediate pro-inflammatory effects including constriction of airways ad smooth muscle contraction.

Items 1-10 of 17

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  1. Zafirlukast
    B2068 Zafirlukast
    Target: Leukotriene and Related Receptors
    Summary: oral leukotriene receptor antagonist
      ≥23.9 mg/mL
  2. LY171883
    C3110 LY171883
    Summary: leukotriene D4 receptor antagonist, orally active
      ≤25 mg/mL
  3. HAMI3379
    C3082 HAMI3379
    Summary: CysLT2 receptor antagonist
      ≤5 mg/mL
  4. ARM1
    C4323 ARM1
    Summary: LTB4 synthesis inhibitor
      ≤1 mg/mL
  5. 5(S),6(R)-7-trihydroxymethyl Heptanoate
    C4837 5(S),6(R)-7-trihydroxymethyl Heptanoate
    Summary: inhibits leukotriene B4 (LTB4)-induced polymorphonuclear neutrophils (PMN) chemotaxis
      ≤50 mg/mL
  6. LY223982
    C4677 LY223982
    Summary: potent BLT1 receptor antagonist
      ≤0.1 mg/mL
  7. γ-Linolenic Acid methyl ester
    C5226 γ-Linolenic Acid methyl ester
    Summary: weak leukotriene B4 (LTB4) receptor antagonist
      ≤100 mg/mL
  8. MK-571 sodium salt hydrate
    B8031 MK-571 sodium salt hydrate
     3 Citation
    Target: CysLT1
    Summary: CysLT1 receptor antagonist
      ≥10.3 mg/mL
  9. FPL 55712
    B6999 FPL 55712
    Summary: Leukotriene receptor antagonist
  10. Leukotriene B4
    B7011 Leukotriene B4
    Summary: BLT1/BLT2 receptor agonist
      Soluble in ethanol

Items 1-10 of 17

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