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EGFR

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

A3320 CO-1686 (AVL-301)

1 Citation

Target: EGFR

Summary: EGFR inhibitor

≥27.8 mg/mL
A3397 Erlotinib

4 Citation

Summary: EGFR tyrosine kinase inhibitor

insoluble in H2O; ≥19.65 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
A3482 Icotinib Hydrochloride

Summary: EGFR inhibitor,potent and specific

Soluble in DMSO
A3256 BMS-690514

Summary: HER/EGFR inhibitor

Soluble in DMSO
B1103 Mutant EGFR inhibitor

Summary: Selective Mutated EGFR inhibitor

Soluble in DMSO
B1496 Icotinib

Summary: EGFR tyrosine kinase inhibitor

insoluble in H2O; ≥129.6 mg/mL
B1104 AZD-9291

1 Citation

Target: EGFR

Summary: Mutated forms EGFR inhibitor

≥24.98 mg/mL
B1105 AZD-9291 mesylate

Summary: third generation EGFRm inhibitor, oral and irreversible

insoluble in EtOH; insoluble in DMSO; insoluble in H2O
A8365 Varlitinib (ARRY334543)

Summary: ErbB inhibitor

≥23.35 mg/mL