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P-gp

P-gp (P-glycoprotein) is a ATP-binding cassette transproters which overepxressed in multidrug-resistance cancer cells. It functions in pumping drug out of cell and lower intracellular drug concentration.

9 Items

per page
  1. Tariquidar methanesulfonate, hydrate
    A3859 Tariquidar methanesulfonate, hydrate
    Target: P-glycoprotein (P-gp)
    Summary: P-glycoprotein inhibitor, potent and selective
      insoluble in H2O; insoluble in EtOH; ≥56.2 mg/mL
  2. Zosuquidar
    A3956 Zosuquidar
    Target: P-glycoprotein (P-gp)|Cytochrome P450 (CYP450)
    Summary: MDR modulator
      Soluble in DMSO
  3. Tariquidar
    A8208 Tariquidar
     2 Citation
    Target: P-glycoprotein (P-gp)
    Summary: P-glycoprotein inhibitor,potent and non-competitive
      insoluble in H2O; insoluble in EtOH; ≥16.17 mg/mL
  4. Dofequidar fumarate
    B1167 Dofequidar fumarate
    Summary: MDR reversal agent
      Soluble in DMSO
  5. LY335979 (Zosuquidar 3HCL)
    A8549 LY335979 (Zosuquidar 3HCL)
     1 Citation
    Target: P-glycoprotein (P-gp)
    Summary: Pgp (P-glycoprotein) inhibitor
      insoluble in EtOH; ≥17.1 mg/mL
  6. Rhodamine 123 (chloride)
    C3140 Rhodamine 123 (chloride)
    Summary: membrane-permeable cationic dye used as substrate for the efflux pump P-glycoprotein
  7. Hypophyllanthin
    C3610 Hypophyllanthin
    Summary: P-glycoprotein (P-gp) inhibitor
      ≤0.2 mg/mL
  8. Estradiol 3-(β-D-Glucuronide) (sodium salt)
    C3897 Estradiol 3-(β-D-Glucuronide) (sodium salt)
    Summary: substrate for multidrug resistance protein 2 (MRP2)
      ≤20 mg/mL
  9. Estradiol 17-(β-D-Glucuronide) (sodium salt)
    C3840 Estradiol 17-(β-D-Glucuronide) (sodium salt)
    Summary: substrate of the multidrug resistance protein 2 (MRP2)
      ≤20 mg/mL

9 Items

per page