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CYP3A/CYP450

CYP3A4 is an enzyme of cytochrome P450 superfamily found in human liver. It catalyzes the metabolism of endogenous and exogenous agents ( e.g. xenobiotics).

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  1. 4β-hydroxy Cholesterol
    C5540 4β-hydroxy Cholesterol
    Summary: marker for CYP3A4/5 activity
      ≤20 mg/mL
  2. YM 511
    B5405 YM 511
    Summary: aromatase (CYP19) inhibitor
      <35.42 mg/mL
  3. 3-Cyano-7-ethoxycoumarin
    B7714 3-Cyano-7-ethoxycoumarin
    Summary: Fluorescent P450 substrate
      Soluble in DMSO
  4. ABT
    B7737 ABT
    Summary: Cytochrome P450 inhibitor
      ≥12.93 mg/mL
  5. Methoxyresorufin
    B5723 Methoxyresorufin
    Summary: fluorometric substrate of cytochrome P450
      insoluble in DMSO
  6. Pentoxyresorufin
    B5724 Pentoxyresorufin
    Summary: fluorometric cytochrome P450 substrate
      insoluble in ethanol;insoluble in DMSO
  7. TMS
    B6768 TMS
    Summary: cytochrome P450 1B1 inhibitor
      Soluble in DMSO

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