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KRAS-PDEδ

PDEδ is a GDI-like solubilizing factor, which regulates the farnesylated KRAS signaling. KRAS-PDEδ interaction is a drug target for cancer treatment.

A3358 Deltarasin

Target: Phosphodiesterases (PDEs)

Summary: KRAS-PDEδ interaction inhibitor

Soluble in DMSO
B1261 Deltarasin hydrochloride

Summary: inhibitor of KRAS-PDEδ interaction, potent and selective

Soluble in DMSO
B5841 AMG-47A

Summary: destabilizer of the KRAS oncoprotein

Soluble in DMSO