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Microbiology & Virology

Virology

A virus is a small infectious agent that replicates inside living cells. Viruses cause many human diseases from small illnesses, like influenza, to more deadly diseases, like hepatitis B and HIV. Our body’s immune system defends against viral infection by generating specific antibodies to bind to and neutralize viral particles and by cell mediated immunity that destroys infected host cells. read more

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  1. VX-222 (VCH-222, Lomibuvir)
    A4032 VX-222 (VCH-222, Lomibuvir)
    Target: HCV polymerase
    Summary: NNI of HCV RNA polymerase
      ≥44.6 mg/mL
  2. Amprenavir (agenerase)
    A8201 Amprenavir (agenerase)
    Summary: HIV-1 protease inhibitor
  3. Ascomycin(FK 520)
    A3191 Ascomycin(FK 520)
    Target: phosphatases
    Summary: Macrolide immunosuppressant,FK-520 analog
      ≥38.9 mg/mL
  4. BMS-626529
    A3253 BMS-626529
     2 Citation
    Target: HIV-1 gp120
    Summary: HIV-1 attachment inhibitor
      insoluble in H2O; insoluble in EtOH; ≥1.48 mg/mL
  5. DDD107498
    A8711 DDD107498
     2 Citation
    Target: Eukaryotic elongation factors
    Summary: A novelmultiple-stage antimalarial agent
      insoluble in H2O; ≥14.05 mg/mL

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