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5-HT Receptor

5-HT receptor (5-hydroxytryptamine receptors) is a group of GPCRs (G protein-coupled receptors) and LGICs (ligand-gated ion channels) found in the central and peripheral nervous systems.

Items 1-10 of 16

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  1. Clozapine N-oxide (CNO)
    A3317 Clozapine N-oxide (CNO)
     1 Citation
    Target: DREADD Ligands
    Summary: Metabolite of clozapine, used in chemogenetics.
      insoluble in EtOH; ≥17.15 mg/mL
  2. SEA0400
    A3811 SEA0400
     4 Citation
    Target: Na /Ca2 Exchangers (NCXs)
    Summary: Specific inhibitor of Na+/Ca2+ exchange
      insoluble in H2O; ≥18.57 mg/mL
  3. Olanzapine
    B2240 Olanzapine
    Target: 5-HT2 Receptors|D2 Receptors
    Summary: Antagonist of 5-HT2A and dopamine D2 receptors
      insoluble in H2O; ≥15.6 mg/mL
  4. Loxapine
    B1001 Loxapine
     1 Citation
    Target: 5-HT2 Receptors
    Summary: 5-HT receptor antagonist
      Soluble in DMSO
  5. Lurasidone HCl
    B1477 Lurasidone HCl
    Target: 5-HT2 Receptors|D2 Receptors|5-HT1 Receptors|5-HT7 Receptors
    Summary: Dopamine D2/5-HT2A/5-HT7/5-HT1A inhibitor
      insoluble in H2O; insoluble in EtOH; ≥11.11 mg/mL
  6. Fluvoxamine
    B1205 Fluvoxamine
    Target: Serotonin reuptake
    Summary: Selective serotonin reuptake inhibitor
      insoluble in H2O; ≥15.92 mg/mL
  7. Pizotifen
    B1206 Pizotifen
    Target: 5-HT2 Receptors
    Summary: Highly selective 5-HT receptor blocking agent
      insoluble in H2O; ≥14.77 mg/mL
  8. Pizotifen Malate
    B2007 Pizotifen Malate
    Target: 5-HT2 Receptors|D2 Receptors
    Summary: 5-HT receptor antagonist
      ≥21.48 mg/mL
  9. Amitriptyline HCl
    B2231 Amitriptyline HCl
    Target: Trk Receptors|5-HT2 Receptors|Norepinephrine transporter|5-HT Transporters
    Summary: Serotonin /norepinephrine receptor/5-HT4/5-HT2 inhibitor
      ≥15.69 mg/mL
  10. Desvenlafaxine
    B2236 Desvenlafaxine
    Target: 5-HT Transporters|Norepinephrine transporters
    Summary: serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor
      insoluble in EtOH; ≥13.2 mg/mL

Items 1-10 of 16

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