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mTOR

MTOR (mechanistic target of rapamycin) is a serine/threonine kinase that regulates cellular metabolism, growth ad survival. It mediates the cellular response to stress, growth factor and hormone etc. It is involved in cancer, aging and neurodegenerative diseases etc.

Items 1-10 of 29

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  1. LY 303511
    A3568 LY 303511
    Summary: MTOR inhibitor
      Soluble in DMSO
  2. GDC-mTOR inhibitor
    A3637 GDC-mTOR inhibitor
    Summary: MTOR inhibitor
      Soluble in DMSO
  3. Nordihydroguaiaretic acid
    A3664 Nordihydroguaiaretic acid
    Summary: Anti-tumor agent;lipoxygenase inhibitor
  4. XL388
    A3940 XL388
    Summary: MTOR inhibitor,highly potent and selective
      insoluble in EtOH; insoluble in H2O; ≥6.87 mg/mL
  5. WYE-687
    B1638 WYE-687
    Summary: MTOR inhibitor,ATP-competitive and selective
      insoluble in H2O; insoluble in EtOH; insoluble in DMSO
  6. Ridaforolimus (Deforolimus, MK-8669)
    B1639 Ridaforolimus (Deforolimus, MK-8669)
    Target: mTOR
    Summary: MTOR inhibitor
      ≥49.5 mg/mL
  7. WAY-600
    B1641 WAY-600
    Target: mTOR
    Summary: MTOR inhibitor
      ≥12.38 mg/mL
  8. AZD2014
    A8373 AZD2014
    Summary: Novel mTOR inhibitor
      ≥23.15 mg/mL
  9. INK 128 (MLN0128)
    A8551 INK 128 (MLN0128)
     4 Citation
    Target: mTOR
    Summary: MTOR(TORC-1/-2) inhibitor,potent and selective
      insoluble in H2O; ≥15.45 mg/mL
  10. GSK2126458
    A8556 GSK2126458
     1 Citation
    Target: PI3K|mTOR
    Summary: PI3K/mTOR inhibitor
      ≥25.3 mg/mL

Items 1-10 of 29

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