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GSK-3

GSK3 (glycogen synthase kinase-3) is a serine/threonine protein kinase which contributes to cell survival, diabetes, insulin resistance and Alzheimer's diseases.

A3570 LY2090314

Target: GSK-3

Summary: Potent GSK-3 inhibitor

insoluble in H2O; ≥91 mg/mL
A3184 AR-A014418

2 Citation

Target: GSK-3

Summary: GSK3β inhibitor, ATP-competitive and selective

insoluble in EtOH; insoluble in H2O; ≥15.4 mg/mL
B1536 AZD1080

1 Citation

Target: GSK-3

Summary: GSK3βinhibitor

insoluble in H2O; insoluble in EtOH; ≥16.7 mg/mL
B1539 Tideglusib

1 Citation

Summary: non-ATP-competitive GSK-3β inhibitor

insoluble in EtOH; insoluble in H2O; ≥16.7 mg/mL
B1538 GSK-3 Inhibitor IX (BIO)

Summary: GSK-3α/GSK-3β inhibitor, cell-permeable, ATP-competitive and reversible
A8395 CHIR-98014

Target: GSK-3

Summary: GSK-3β inhibitor,selective and ATP-competitive

insoluble in H2O; insoluble in EtOH; ≥8.1 mg/mL
A8396 CHIR-99021 (CT99021) HCl

Target: GSK-3

Summary: GSK-3α/β inhibitor

≥25.1 mg/mL
A3011 CHIR-99021 (CT99021)

2 Citation

Target: GSK-3

Summary: GSK-3 inhibitor, Cell-permeable, ATP-competitive

≥23.27 mg/mL
B1540 TWS119

1 Citation

Summary: GSK-3β inhibitor

insoluble in H2O; insoluble in EtOH; ≥15.9 mg/mL
B1249 TDZD-8

1 Citation

Summary: GSK-3β inhibitor

insoluble in H2O; ≥11.1 mg/mL