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Smoothened

Smoothened is a G protein-coupled receptor of the hedgehog signaling pathway.

A3460 HhAntag

Summary: GLI1-mediated transcription inhibitor

insoluble in H2O; ≥13.3 mg/mL
A3543 LDE225 Diphosphate

Target: Smoothened

Summary: Smo antagonist

≥27.85 mg/mL
A3258 BMS-833923

Target: Smoothened

Summary: Smoothened inhibitor

≥47.4 mg/mL
B2266 LDE225 (NVP-LDE225,Erismodegib)

1 Citation

Target: Smoothened

Summary: Smoothened inhibitor,potent and selective

≥24.3 mg/mL
B3283 PF-04449913

Target: Smoothened

Summary: Antagonist of smoothened

≥20.15 mg/mL
A8228 Purmorphamine

Summary: Hedgehog agonist
C4582 ALLO-1

Summary: SMO antagonist

≤20 mg/mL
B5674 SMANT hydrochloride

Summary: Smoothened (Smo) signaling inhibitor

<7.51 mg/mL
B5766 M 25

Summary: Smoothened (Smo) receptor antagonist

<37.95 mg/mL
B5767 GSA 10

Summary: Smoothened (Smo) receptor agonist

soluble in DMSO