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Bcr-Abl

Bcl-Abl is a constitutively activated chimeric tyrosine kinase which is the genetic abnormality expressed in patient with CML (chronic myeloid leukemia).

Items 1-10 of 16

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  1. Nilotinib monohydrochloride monohydrate
    A3660 Nilotinib monohydrochloride monohydrate
    Summary: Bcr-Abl inhibitor
      ≥50 mg/mL
  2. GNF 2
    A8603 GNF 2
    Summary: Bcr-Abl inhibitor
      insoluble in H2O; ≥18.7 mg/mL
  3. GNF 5
    A8604 GNF 5
    Target: Bcr-Abl
    Summary: Bcr-Abl inhibitor
  4. 1-Naphthyl PP1
    A8605 1-Naphthyl PP1
    Summary: Src family kinases inhibitor
      Soluble in DMSO
  5. PD 180970
    A8606 PD 180970
    Summary: P210bcr/abl tyrosine kinase inhibitor
      <21.46 mg/mL
  6. PPY A
    A8607 PPY A
    Target: Abl kinases
    Summary: Abl kinases inhibitor
      <37.24 mg/mL
  7. PD173955
    A8812 PD173955
    Target: Bcr-Abl|Src
    Summary: Dual Src/Abl kinase inhibitor, ATP-competitive,
      ≥22.15 mg/mL
  8. Dasatinib (BMS-354825)
    A3017 Dasatinib (BMS-354825)
     4 Citation
    Summary: Src and BCR-Abl inhibitor
      ≥24.4 mg/mL
  9. Bafetinib (INNO-406)
    B1011 Bafetinib (INNO-406)
     2 Citation
    Summary: Bcr-Abl/Lyn tyrosine kinase inhibitor
      ≥57.7 mg/mL
  10. DCC-2036 (Rebastinib)
    B1404 DCC-2036 (Rebastinib)
    Target: FLT3|Bcr-Abl|Tie-2|KDR
    Summary: Bcr-Abl inhibitor
      ≥27.7 mg/mL

Items 1-10 of 16

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