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ROCK

ROCK (Rho-associated protein kinase) is a kinase belonging to the AGC family of serine-threonine kinases and takes part in regulating the shape and movement of cells by acting on the cytoskeleton.

A3478 Hydroxyfasudil

Target: ROCK|Rho-kinase

Summary: Rho-kinase inhibitor and vasodilator

Soluble in DMSO
A3771 RKI-1447

Target: ROCK

Summary: Potent ROCK1/ROCK2 inhibitor

insoluble in H2O; ≥16.3 mg/mL
A3825 SLx-2119

1 Citation

Target: ROCK

Summary: Selective ROCK2 inhibitor

≥22.65 mg/mL
A3008 Y-27632 dihydrochloride

19 Citation

Target: ROCK

Summary: ROCK1 inhibitor

≥111.2 mg/mL
A5611 GSK429286A

Target: ROCK

Summary: Selective ROCK1/ROCK2 inhibitor

≥21.6 mg/mL
A5734 Fasudil (HA-1077) HCl

1 Citation

Target: ROCK

Summary: Protein kinase inhibitor

≥16.4 mg/mL
B7807 Netarsudil (AR-13324)

Target: ROCK

Summary: ROCK inhibitor

≥26.3 mg/mL
B3392 GSK269962A

Target: ROCK|RSK|MSK

Summary: ROCK inhibitor

Soluble in DMSO