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TGF-βR1(ALK5)

TGF-βR1 (transforming growth factor beta receptors) are a serine/threonine protein kinase that involved in the regulation of cell cycle arrest, cell proliferation and differentiation, production of extracellular matrix, wound healing, tumorgenesis and immunosuppression etc.

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  1. SB-505124 hydrochloride
    A3799 SB-505124 hydrochloride
    Target: ALK
    Summary: ALK5/ALK4/ALK7 inhibitor in TGF-β/activin signalling,selective
  2. SD-208
    A3808 SD-208
    Summary: TGF-βR I kinase inhibitor
      ≥8.95 mg/mL
  3. A 77-01
    A3132 A 77-01
    Summary: Potent ALK5 inhibitor
      insoluble in H2O; ≥14.3 mg/mL
  4. A 83-01
    A3133 A 83-01
    Summary: ALK-5 inhibitor
      ≥21.1 mg/mL
  5. LY2109761
    A8464 LY2109761
     4 Citation
    Summary: TβRI/II kinase inhibitor
      ≥22.1 mg/mL
  6. K02288
    B2286 K02288
    Target: ALK
    Summary: ALK inhibitor
      insoluble in H2O; ≥17.6 mg/mL
  7. SB 431542
    A8249 SB 431542
     2 Citation
    Summary: ALK inhibitor
  8. SB525334
    A5602 SB525334
    Summary: (TGF-beta1) receptor inhibitor
      ≥34.3 mg/mL
  9. GW788388
    A8301 GW788388
    Summary: ALK5 inhibitor,potent and selective
      ≥21.25 mg/mL
  10. LY2157299
    A8348 LY2157299
     2 Citation
    Summary: TGF-βR1 inhibitor,potent and selective
      insoluble in H2O; ≥18.45 mg/mL

Items 1-10 of 14

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