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ALK

ALK (anaplastic lymphoma kinase) is a member of insulin receptor protein-tyrosine superfamily, functioning in embryonic development and involved in cell survival and cell fate.

8 Items

per page
  1. GSK1838705A
    A8440 GSK1838705A
    Target: Insulin and Insulin-like Receptors|ALK
    Summary: IGF-IR/IR/ALK inhibitor, ATP-competitive
      ≥26.65 mg/mL
  2. CH5424802
    A8393 CH5424802
    Target: ALK
    Summary: ALK inhibitor,potent and ATP-competitive
  3. AZD-3463
    A8620 AZD-3463
     3 Citation
    Target: ALK|Insulin-like growth factors (IGFs)
    Summary: ALK/IGF1R inhibitor
      insoluble in H2O; insoluble in EtOH; ≥11.22 mg/mL
  4. (R)-Crizotinib
    A3020 (R)-Crizotinib
     2 Citation
    Target: c-MET
    Summary: C-MET/ALK inhibitor,potent and ATP-competitve
      insoluble in H2O; insoluble in EtOH; ≥7.51 mg/mL
  5. LDK378
    A8328 LDK378
    Target: ALK
    Summary: Potent ALK inhibitor
      insoluble in H2O; ≥13.95 mg/mL
  6. Entrectinib
    B5859 Entrectinib
    Target: Trk Receptors|ALK|ROS1
    Summary: Orally active inhibitor of ALK kinase
      ≥28.05 mg/mL
  7. PF-06463922
    B4882 PF-06463922
    Target: ALK|ROS1
    Summary: ALK/ROS1 inhibitor,potent and selective
      insoluble in H2O; ≥20.3 mg/mL
  8. DMH-1
    B3686 DMH-1
    Target: BMP and Other Activin Receptors
    Summary: Selective BMP ALK2 receptor
      insoluble in H2O; insoluble in EtOH; ≥9.51 mg/mL

8 Items

per page