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FGFR

FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.

A3378 E-3810

Summary: VEGF/FGF dual inhibitor, potent and selective

Soluble in DMSO
A3576 LY2874455

Summary: FGF/FGFR Inhibitor

≥44.4 mg/mL
A3673 NVP-BGJ398 phosphate

Summary: FGFR inhibitor

insoluble in EtOH; ≥28.07 mg/mL
A4116 Danusertib (PHA-739358)

2 Citation

Target: Aurora Kinases

Summary: Pan-aurora kinase inhibitor

≥23.75 mg/mL
A3014 BGJ398

1 Citation

Target: FGFR

Summary: FGFR inhibitor ,potent and selective

insoluble in H2O; insoluble in EtOH; ≥7 mg/mL
A3022 Pazopanib (GW-786034)

Target: CSF-1R|VEGFR|PDGFR|c-Kit|FGFR

Summary: VEGFR/PDGFR/FGFR inhibitor

insoluble in EtOH; insoluble in H2O; ≥10.95 mg/mL
A8237 SKLB610

Summary: Potent VEGFR inhibitor

insoluble in H2O; ≥20.75 mg/mL
A8252 Nintedanib (BIBF 1120)

3 Citation

Target: VEGFR|PDGFR|FGFR

Summary: VEGFR/PDGFR/FGFR inhibitor

insoluble in H2O; insoluble in EtOH; ≥5.34 mg/mL
A8253 PD 173074

Target: VEGFR|FGFR

Summary: FGFR inhibitor

≥26.18 mg/mL
A2168 Dovitinib (TKI-258, CHIR-258)

2 Citation

Target: FLT3|VEGFR|PDGFR|c-Kit|FGFR

Summary: Multitargeted RTK inhibitor

insoluble in H2O; insoluble in EtOH; ≥36.35 mg/mL