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FLT3

FLT3 (FMS-like tyrosine kinase 3) is a cytokine receptor which belongs to the receptor tyrosine kinase class III and plays a role in cell survival, proliferation, and differentiation.

9 Items

per page
  1. Silvestrol
    A3818 Silvestrol
    Summary: Antineoplastic
      Soluble in DMSO
  2. SU5416
    A3847 SU5416
    Target: VEGFR
    Summary: VEGF receptor inhibitor and AHR agonist
      insoluble in EtOH; insoluble in H2O; ≥11.9 mg/mL
  3. KW 2449
    A4123 KW 2449
    Target: Aurora Kinases|FLT3|Bcr-Abl
    Summary: Multikinase inhibitor
      insoluble in EtOH; insoluble in H2O; ≥16.6 mg/mL
  4. AST 487
    A3194 AST 487
     1 Citation
    Target: RET
    Summary: RET kinase inhibitor
      ≥26.5 mg/mL
  5. Linifanib (ABT-869)
    A2949 Linifanib (ABT-869)
    Target: VEGFR|PDGFR
    Summary: VEGFR/PDGFR inhibitor
      insoluble in H2O; insoluble in EtOH; ≥18.75 mg/mL
  6. Ponatinib (AP24534)
    A5467 Ponatinib (AP24534)
     1 Citation
    Target: VEGFR|PDGFR|Bcr-Abl|FGFR|Src
    Summary: pan-BCR-ABL inhibitor,multi-kinase inhibitor
      ≥53.3 mg/mL
  7. Quizartinib (AC220)
    A5793 Quizartinib (AC220)
    Target: FLT3
    Summary: FLT3 inhibitor,potent and selective
      ≥28.03 mg/mL
  8. G-749
    A8889 G-749
    Target: Aurora Kinases|FLT3|c-RET
    Summary: FLT3 inhibitor
      ≥26.05 mg/mL
  9. UNC2025
    B8016 UNC2025
     1 Citation
    Target: MER|FLT3
    Summary: orally bioavailable dual MER/FLT3 inhibitor
      ≥23.85 mg/mL

9 Items

per page