Anamorelin
Catalog No.
A3179
Ghrelin receptor agonist, synthetic, orally active
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Anamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite.
| Storage | Store at -20°C |
| M.Wt | 546.7 |
| Cas No. | 249921-19-5 |
| Formula | C31H42N6O3 |
| Synonyms | RC-1291;ONO-7643;RC1291;ONO7643;RC 1291;ONO 7643 |
| Solubility | insoluble in H2O; ≥20.52 mg/mL in EtOH; ≥91.4 mg/mL in DMSO |
| Chemical Name | 2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide |
| SDF | Download SDF |
| Canonical SMILES | CC(C)(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)N3CCCC(C3)(CC4=CC=CC=C4)C(=O)N(C)N(C)C)N |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
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