Dapivirine (TMC120)
Catalog No.
A8554
Nonnucleoside reverse transcriptase inhibitor
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Dapivirine (DPV) is a nonnucleoside reverse transcriptase inhibitor with a favorable safety profile following vaginal application.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 329.4 |
| Cas No. | 244767-67-7 |
| Formula | C20H19N5 |
| Synonyms | TMC 120;TMC-120 |
| Solubility | insoluble in H2O; ≥13.5 mg/mL in DMSO; ≥5.41 mg/mL in EtOH |
| Chemical Name | 4-[[4-(2,4,6-trimethylanilino)pyrimidin-2-yl]amino]benzonitrile |
| SDF | Download SDF |
| Canonical SMILES | CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
| Description | Dapivirine (TMC120) is a non-nucleoside inhibitor of HIV reverse transcriptase with an IC50 vaule of 24 nM. | |||||
| Targets | HIV reverse transcriptase | |||||
| IC50 | 24 nM | |||||
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
