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Glibenclamide

Catalog No.
B1296
Insulin production modulator
Grouped product items
Size Price Stock Qty
10mM (in 1mL DMSO)
Special Price $24.75 Regular Price $55.00
In stock
1g
Special Price $22.50 Regular Price $50.00
In stock
5g
Special Price $36.00 Regular Price $80.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

Glibenclamide is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt494
Cas No.10238-21-8
FormulaC23H28ClN3O5S
Solubility≥49.4 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
Chemical Name5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
SDFDownload SDF
Canonical SMILESCOC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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