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GRI 977143

Catalog No.
A4471
LPA2 receptor non-lipid agonist
Grouped product items
Size Price Stock Qty
1mg
Special Price $31.50 Regular Price $70.00
Ship with 5-10 days
50mg
Special Price $580.50 Regular Price $1,290.00
Ship with 5-10 days
5mg
Special Price $85.50 Regular Price $190.00
Ship with 5-10 days
10mg
Special Price $155.25 Regular Price $345.00
Ship with 5-10 days
25mg
Special Price $342.00 Regular Price $760.00
Ship with 5-10 days
For scientific research use only and should not be used for diagnostic or medical purposes.

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Background

Selective lysophosphatidic acid 2 (LPA2) receptor non-lipid agonist (EC50 = 3.3 μM). Does not activate other LPA GPCRs at concentrations up to 10 μM. Antiapoptotic; inhibits activation of caspases 3, 7, 8 and 9, Bax translocation and PARP-1 cleavage. Activates ERK1/2 survival pathway.

Chemical Properties

Physical AppearanceWhite solid
StorageStore at 4°C
M.Wt391.44
Cas No.325850-81-5
FormulaC22H17NO4S
SolubilitySoluble in DMSO
Chemical Name2-[3-(1,3-dioxobenzo[de]isoquinolin-2-yl)propylsulfanyl]benzoic acid
SDFDownload SDF
Canonical SMILESC1=CC=C(C(=C1)C(=O)O)SCCCN2C(=O)C3=CC=CC4=C3C(=CC=C4)C2=O
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

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Chemical structure

GRI 977143