Influenza A virus fragment
Influenza A virus fragment has the RNA sequence of Leu-Lys-Phe-Ala-Phe-Ser-Met-Met.
Influenzavirus A is a genus of the Orthomyxoviridae family of viruses. Some isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Influenza A viruses are negative-sense, single-stranded, segmented RNA viruses. The several subtypes are labeled according to an H number (for the type of hemagglutinin) and an N number (for the type of neuraminidase).
The Influenza A virus genome is contained on eight single (non-paired) RNA strands that code for eleven proteins (HA, NA, NP, M1, M2, NS1, NEP, PA, PB1, PB1-F2, PB2).
Figure 1: Scheme of Influenza A virus
Ref:
1. "Avian influenza (" bird flu") — Fact sheet". WHO.
2. "Unique new flu virus found in bats". NHS Choices. 1 March 2012. Retrieved 16 May 2012.
3. Gewin, V. (2012). "Bats harbour influenza". Nature.
4. Tong, S.; Li, Y.; Rivailler, P.; Conrardy, C.; Castillo, D. A. A.; Chen, L. -M.; Recuenco, S.; Ellison, J. A. et al. (2012). "A distinct lineage of influenza a virus from bats". Proceedings of the National Academy of Sciences.
5. MicrobiologyBytes: Virology: Orthomyxoviruses
6. Subbarao, K.; Joseph, T. (2007). “Scientific barriers to developing vaccines against avian influenza viruses”. Nature Reviews Immunology 7, 267-278.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 974.24 |
| Formula | C46H71N9O10S2 |
| Synonyms | H2N-Leu-Lys-Phe-Ala-Phe-Ser-Met-Met-OH |
| Solubility | ≥88.7 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH |
| SDF | Download SDF |
| Canonical SMILES | CC(CC(C(NC(CCCCN)C(NC(CC1=CC=CC=C1)C(NC(C)C(NC(CC2=CC=CC=C2)C(NC(CO)C(NC(CCSC)C(NC(CCSC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)N)C |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
