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  • Search results for: 'research area apoptosis bcl 2 family'

Search results for: 'research area apoptosis bcl 2 family'

Items 31-40 of 154

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  1. SMIP004
    A3826 SMIP004
    Summary: Apoptosis inducer
      insoluble in H2O; ≥20.5 mg/mL
  2. YM155
    A4221 YM155
     2 Citation
    Target: Survivin
    Summary: Survivin suppressant,apoptosis inhibitor
      ≥22.15 mg/mL
  3. Z-VAD-FMK
    A1902 Z-VAD-FMK
     102 Citation
    Target: Caspases
    Summary: Cell-permeable, irreversible pan-caspase inhibitor
      ≥23.37 mg/mL
  4. Pifithrin-μ
    A4482 Pifithrin-μ
     1 Citation
    Target: Autophagy|p53|HSP70
    Summary: Inhibitor of p53 binding and anti-apoptotic
      insoluble in H2O; ≥18.1 mg/mL
  5. R18
    A4446 R18
    Summary: 14.3.3 proteins Antagonist
      Soluble to 1 mg/mL
  6. PAC-1
    A8177 PAC-1
     1 Citation
    Target: Caspases
    Summary: Procaspase-3 activator
      insoluble in H2O; ≥13.4 mg/mL
  7. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL
  8. PRIMA-1
    A4483 PRIMA-1
    Target: p53
    Summary: BAX inhibitor
      ≥110.6 mg/mL
  9. PD-1/PD-L1 inhibitor 2
    B6023 PD-1/PD-L1 inhibitor 2
    Target: PD-1/PD-L1 interaction
    Summary: PD-1/PD-L1 interaction inhibitor
      ≥42 mg/mL
  10. Nutlin-3
    A4228 Nutlin-3
    Target: MDM2
    Summary: MDM2 antagonist,inhibits MDM2-p53 interaction
      ≥58.2 mg/mL

Items 31-40 of 154

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  1. Category Apoptosis Remove This Item
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Category
  1. Caspase 25item
  2. 14.3.3 Proteins 1 item
  3. Apoptosis Inducers 38item
  4. Bax 6item
  5. Bcl-2 Family 24item
  6. Bcl-xL 8item
  7. c-RET 8item
  8. IAP 8item
  9. KEAP1-Nrf2 4item
  10. MDM2 6item
  11. p53 23item
  12. PC-PLC 1 item
  13. PKD 4item
  14. RasGAP (Ras- P21) 1 item
  15. Survivin 2item
  16. Thymidylate Synthase 2item
  17. TNF-α 6item
  18. Other Apoptosis 6item
  19. PD-1/PD-L1 interaction 1 item
  20. ASK1 2item
  21. PAR4 1 item
  22. Apoptosis 1 item
Specificity
  1. Selective 43item
Reversibility
  1. Reversible 1 item
  2. Irreversible 8item
Target
  1. Caspases 13item
  2. Proteasome 1 item
  3. Histone Deacetylases (HDACs) 2item
  4. Inhibitor of apoptosis proteins (IAP) 3item
  5. Bcl-2 8item
  6. Raf 2item
  7. Aurora Kinases 1 item
  8. Bcl-xl 3item
  9. MDM2 2item
  10. VEGFR 3item
  11. PDGFR 3item
  12. c-Kit 2item
  13. RET 1 item
  14. Mcl-1 4item
  15. Thymidylate Synthase 1 item
  16. Bcr-Abl 1 item
  17. Nrf2 1 item
  18. Sir2-like Family Deacetylases (Sirtuins) 1 item
  19. Deubiquitinating enzymes (DUBs) 1 item
  20. Aminopeptidases 1 item
  21. RIP kinases 1 item
  22. PD-1/PD-L1 interaction 1 item
  23. Topoisomerases 1 item
  24. Survivin 1 item
  25. Dehydrogenase 1 item
  26. Autophagy 1 item
  27. COX 1 item
  28. iNOS 1 item
  29. TRP Channel 1 item
  30. Apoptosis Inducers 1 item
  31. angiogenesis 1 item
  32. c-RET 1 item
  33. FPTase 1 item
  34. Bfl-1 1 item
  35. p53-MDM2 interaction 1 item
  36. p53 5item
  37. cysteine protease 1 item
  38. HDM2 ubiquitin ligase 1 item
  39. PC-PLC 1 item
  40. HIV 1 item
  41. Histone Acetyltransferases (HATs) 1 item
  42. Telomerases 1 item
  43. Tyrosinases 1 item
  44. HSP70 1 item
  45. p21 1 item
  46. DHFR 1 item
  47. GARFT 1 item
  48. PKD 1 item
  49. Bcl-w 1 item
  50. Bax 1 item
  51. NS3/4a Proteases 1 item
Reported Experiments
  1. Animal Experiments 56item
  2. Cell Experiments 46item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Adrenocortical Carcinoma 1 item
  3. Autoimmune Diseases 1 item
  4. Breast Cancer 8item
  5. Cancer 39item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Chronic Myeloproliferative Disorders 1 item
  8. Colon Cancer 4item
  9. Colorectal Cancer 2item
  10. Glioblastoma 4item
  11. HCV 1 item
  12. Hepatocellular Carcinoma 1 item
  13. Inflammatory Diseases 1 item
  14. Lung Cancer 2item
  15. Lymphoma 4item
  16. Melanoma 2item
  17. Multiple Myeloma 1 item
  18. Myelofibrosis 1 item
  19. Neuroblastoma 1 item
  20. Non-small Cell Lung Cancer 2item
  21. Ovarian Cancer 1 item
  22. Pain Relief 1 item
  23. Pancreatic Cancer 2item
  24. Pentacyclic Triterpenoid 1 item
  25. Prostate Cancer 5item
  26. Pulmonary Fibrosis 1 item
  27. Rheumatoid Arthritis 1 item
  28. Soft Tissue Sarcoma 1 item
  29. Testicular Cancer 1 item