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  • Search results for: 'research area apoptosis bcl xl'

Search results for: 'research area apoptosis bcl xl'

Items 51-60 of 234

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  1. Pifithrin-μ
    A4482 Pifithrin-μ
     1 Citation
    Target: Autophagy|p53|HSP70
    Summary: Inhibitor of p53 binding and anti-apoptotic
      insoluble in H2O; ≥18.1 mg/mL
  2. LCL161
    A3541 LCL161
     1 Citation
    Target: Inhibitor of apoptosis proteins (IAP)
    Summary: Antagonist of IAPs inhibitor
      ≥25.05 mg/mL
  3. 3,3'-Diindolylmethane
    A3118 3,3'-Diindolylmethane
    Summary: Anticancer and antineoplastic agent
      insoluble in H2O; ≥11.15 mg/mL
  4. JNJ-26854165 (Serdemetan)
    A4204 JNJ-26854165 (Serdemetan)
     1 Citation
    Target: p53|HDM2 ubiquitin ligase
    Summary: P53 activator, blocking Mdm2-p53 interaction
      insoluble in EtOH; insoluble in H2O; ≥14.8 mg/mL
  5. Cobimetinib (R-enantiomer)
    A3323 Cobimetinib (R-enantiomer)
    Summary: Selective MEK inhibitor
      Soluble in DMSO
  6. MIRA-1
    A4479 MIRA-1
    Summary: Restorer of wild-type p53 conformation/cellular function
      Soluble in DMSO
  7. Plumbagin
    A4456 Plumbagin
    Summary: Anticancer agent
  8. R18
    A4446 R18
    Summary: 14.3.3 proteins Antagonist
      Soluble to 1 mg/mL
  9. PAC-1
    A8177 PAC-1
     1 Citation
    Target: Caspases
    Summary: Procaspase-3 activator
      insoluble in H2O; ≥13.4 mg/mL
  10. RG7112
    A3762 RG7112
     5 Citation
    Target: MDM2
    Summary: MDM2 inhibitor, first clinical
      ≥36.4 mg/mL

Items 51-60 of 234

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  1. Proteases 24item
  2. Apoptosis 135item
  3. Chromatin/Epigenetics 15item
  4. Metabolism 8item
  5. MAPK Signaling 6item
  6. Tyrosine Kinase 11item
  7. DNA Damage/DNA Repair 9item
  8. PI3K/Akt/mTOR Signaling 3item
  9. Microbiology & Virology 2item
  10. Cell Cycle/Checkpoint 8item
  11. Ubiquitination/ Proteasome 6item
  12. JAK/STAT Signaling 7item
  13. TGF-β / Smad Signaling 2item
  14. Angiogenesis 2item
  15. GPCR/G protein 1 item
  16. Stem Cell 2item
  17. Membrane Transporter/Ion Channel 1 item
  18. Cancer Biology 21item
  19. Endocrinology and Hormones 14item
  20. Neuroscience 11item
  21. Obesity, Appetite Control & Diabetes 4item
  22. Other Signal Transduction 24item
  23. Others 12item
  24. Immunology/Inflammation 10item
  25. Cardiovascular 14item
Specificity
  1. Selective 59item
Reversibility
  1. Reversible 1 item
  2. Irreversible 6item
Target
  1. Caspases 11item
  2. Cyclin-Dependent Kinases 1 item
  3. Proteasome 2item
  4. Histone Deacetylases (HDACs) 4item
  5. Inhibitor of apoptosis proteins (IAP) 2item
  6. Bcl-2 8item
  7. Raf 2item
  8. Aurora Kinases 1 item
  9. Bcl-xl 3item
  10. MDM2 2item
  11. AP-1 1 item
  12. DT-diaphorases 1 item
  13. GSK-3 1 item
  14. VEGFR 3item
  15. PDGFR 3item
  16. c-Kit 2item
  17. RET 1 item
  18. Mcl-1 4item
  19. Thymidylate Synthase 1 item
  20. JNK 1 item
  21. Bcr-Abl 1 item
  22. Nrf2 1 item
  23. Sir2-like Family Deacetylases (Sirtuins) 1 item
  24. Deubiquitinating enzymes (DUBs) 1 item
  25. Smoothened 1 item
  26. Aminopeptidases 1 item
  27. STAT 1 item
  28. RIP kinases 1 item
  29. JAK 4item
  30. HSP90 2item
  31. Topoisomerases 1 item
  32. Survivin 1 item
  33. Ubiquitin-specific proteases 1 item
  34. Melanocortin (MC) Receptors 1 item
  35. Dehydrogenase 1 item
  36. MK2 1 item
  37. Fatty-acid-binding proteins (FABPs) 1 item
  38. Autophagy 1 item
  39. COX 1 item
  40. NADPH Oxidases 1 item
  41. MAGL 1 item
  42. Histamine H1 Receptors 1 item
  43. iNOS 1 item
  44. TRP Channel 1 item
  45. Apoptosis Inducers 1 item
  46. Glucocorticoid Receptors 1 item
  47. Cdc7 1 item
  48. angiogenesis 1 item
  49. c-RET 1 item
  50. FPTase 1 item
  51. Bfl-1 1 item
  52. sodium channels 1 item
  53. p53 4item
  54. cysteine protease 1 item
  55. HDM2 ubiquitin ligase 1 item
  56. PC-PLC 1 item
  57. HIV 1 item
  58. Histone Acetyltransferases (HATs) 1 item
  59. Telomerases 1 item
  60. Tyrosinases 1 item
  61. HSP70 1 item
  62. phosphatidylinositol kinase 1 item
  63. Adenosine Deaminases 1 item
  64. p21 1 item
  65. DHFR 1 item
  66. GARFT 1 item
  67. RHA 1 item
  68. TRPC channel 1 item
  69. PKD 1 item
  70. Bcl-w 1 item
  71. Bax 1 item
  72. NS3/4a Proteases 1 item
Reported Experiments
  1. Animal Experiments 77item
  2. Cell Experiments 64item
Related Disease
  1. Acute Myeloid Leukemia 1 item
  2. Adrenocortical Carcinoma 1 item
  3. Autoimmune Diseases 1 item
  4. Breast Cancer 11item
  5. Cancer 52item
  6. Chronic Lymphocytic Leukemia 1 item
  7. Chronic Myeloproliferative Disorders 1 item
  8. Colon Cancer 5item
  9. Colon Carcinoma 1 item
  10. Colorectal Cancer 3item
  11. Glioblastoma 5item
  12. HCV 1 item
  13. Hepatocellular Carcinoma 1 item
  14. Inflammatory Diseases 2item
  15. Leukemia 2item
  16. Lung Cancer 2item
  17. Lymphoma 4item
  18. Medulloblastoma 1 item
  19. Melanoma 5item
  20. Multiple Myeloma 1 item
  21. Myelofibrosis 1 item
  22. Myeloma 1 item
  23. Neuroblastoma 1 item
  24. Non-small Cell Lung Cancer 3item
  25. Ovarian Cancer 1 item
  26. Pain Relief 1 item
  27. Pancreatic Cancer 3item
  28. Pancreatic Carcinoma 1 item
  29. Pentacyclic Triterpenoid 1 item
  30. Prostate Cancer 8item
  31. Pulmonary Fibrosis 1 item
  32. Rheumatoid Arthritis 2item
  33. Soft Tissue Sarcoma 1 item
  34. Testicular Cancer 1 item
  35. Type 2 Diabetes 2item